Rütt A, Küsswetter W
Z Orthop Ihre Grenzgeb. 1986 Mar-Apr;124(2):140-3. doi: 10.1055/s-2008-1044538.
In more than 15% of the homozygotic patients sickle-cell anemia coincides with severe changes of the skeleton. The skeletal manifestation of the disease is characterized by a generalized osteoporosis and--more typical--by destruction of the epi- and metaphysis caused by osseous infarction. The indication, effectiveness and technical problems of total joint replacement in bilateral destruction of the hipjoints due to sickle-cell anemia are demonstrated.
在超过15%的纯合子患者中，镰状细胞贫血与骨骼的严重变化同时出现。该疾病的骨骼表现特征为全身性骨质疏松，更典型的是骨梗死导致的骨骺和干骺端破坏。本文展示了镰状细胞贫血导致双侧髋关节破坏时全关节置换的适应症、有效性及技术问题。
