Australian Research Centre for Population Oral Health, University of Adelaide, Adelaide, Australia.
Piracicaba Dental School, University of Campinas, Piracicaba, Brazil.
Community Dent Oral Epidemiol. 2023 Dec;51(6):1216-1224. doi: 10.1111/cdoe.12865. Epub 2023 May 11.
Schizophrenia is a disabling mental disorder associated with severe social dysfunction. Individuals with long-term mental conditions have poorer Oral Health-Related Quality of Life (OHRQoL) compared to the general population, but little is known about the measurement properties of OHRQoL instruments in this group of patients. This study aimed to examine the replicability of OHRQoL networks across samples of the general community (GC) and patients with schizophrenia (PWS).
Data were obtained from 603 community-dwelling participants and 627 patients with schizophrenia. OHRQoL was measured using the short form of the Oral Health Impact Profile (OHIP-14) questionnaire. A regularized partial correlation network was estimated for each sample. The number of dimensions and structural stability were assessed using Exploratory Graph Analysis. Global strength, edge weights and centrality estimates were compared. Network replicability was examined fitting the PWS data to the GC network structure.
A single OHIP-14 dimension was identified in the GC sample, whereas three dimensions were detected in the PWS sample. Structural consistency was perfect in the network of GC participants (1), and considerably low in at least two dimensions of the PWS network (0.28; 0.65; 0.16). A moderate correlation for node strength estimates was observed (τ: 0.43; 95% CI: 0.13, 0.72), although edge weights were not correlated (τ: 0.025; 95% CI: -0.11, 0.16). The fit of the PWS data to the GC network structure was deemed unacceptable.
Network models of OHRQoL did not replicate across samples of the general community and outpatients with schizophrenia. Prudent use of OHIP-14 to compare measures of OHRQoL between groups with significant cognitive impartment and the general population is recommended.
精神分裂症是一种致残性精神障碍，与严重的社会功能障碍有关。与一般人群相比，长期患有精神疾病的个体的口腔健康相关生活质量（OHRQoL）较差，但人们对这组患者的 OHRQoL 测量工具的测量特性知之甚少。本研究旨在检验一般人群（GC）和精神分裂症患者（PWS）样本中 OHRQoL 网络的可复制性。
数据来自 603 名社区居民和 627 名精神分裂症患者。OHRQoL 使用口腔健康影响简表（OHIP-14）问卷的简短形式进行测量。为每个样本估计了正则化部分相关网络。使用探索性图分析评估了维度数量和结构稳定性。比较了全局强度、边缘权重和中心性估计值。通过将 PWS 数据拟合到 GC 网络结构来检查网络的可复制性。
在 GC 样本中识别出一个单一的 OHIP-14 维度，而在 PWS 样本中检测到三个维度。GC 参与者网络的结构一致性为完美（1），而 PWS 网络的至少两个维度的结构一致性较低（0.28；0.65；0.16）。观察到节点强度估计值的中等相关性（τ：0.43；95%CI：0.13，0.72），尽管边缘权重不相关（τ：0.025；95%CI：-0.11，0.16）。PWS 数据拟合 GC 网络结构的效果不佳。
一般人群和门诊精神分裂症患者样本中的 OHRQoL 网络模型没有复制。建议在具有明显认知障碍的群体和一般人群之间使用 OHIP-14 来比较 OHRQoL 测量值时，应谨慎使用。
