J Gen Physiol. 2023 Jun 5;155(6). doi: 10.1085/jgp.202313402. Epub 2023 May 11.
JGP study (Gada et al. 2023. J. Gen. Physiol. https://doi.org/10.1085/jgp.202213255) reveals that the membrane lipid PI(4,5)P2 alters the activity of NaV1.4 channels by modulating their gating behavior.
JGP 研究(Gada 等人,2023 年。《普通生理学杂志》。https://doi.org/10.1085/jgp.202213255)表明,膜脂质 PI(4,5)P2 通过调节钠通道的门控行为来改变 NaV1.4 通道的活性。