Müller D, Wolf E
Z Urol Nephrol. 1986 Mar;79(3):159-62.
Within of a for the first time performed aimed study of the early recognition and frequency of the glomerulonephritis in 1,425 males the findings of an "asymptomatic proteinuria" were proved in 5.26% of the affected persons. As a result of a comprehensive investigation, the close of which was in every case the biopsy of the kidney with the histological examination of the renipuncture cylinder, a frequency of glomerulonephritis of 2.8% was found. Within this investigation the findings of an "asymptomatic proteinuria" proved to be the decisive parameter independent of the size of excretion and the reproducibility. The serological investigations did not show any specifity and proved to be insignificant for the early recognition. The results confirm that the diagnosis of "physiological proteinuria" may be made only then when there is an inconspicuous histological finding. In lacking renal histology every form of the proteinuria should at first be attributed to glomerular process.
在首次针对1425名男性进行的肾小球肾炎早期识别及发病率的目标研究中,5.26%的患者被证实存在“无症状蛋白尿”。经过全面调查,每次调查均以肾脏活检及肾穿刺组织学检查为结束,结果发现肾小球肾炎的发病率为2.8%。在此次调查中,“无症状蛋白尿”的发现被证明是一个独立于排泄量大小和再现性的决定性参数。血清学检查未显示任何特异性,且被证明对早期识别无意义。结果证实,只有在组织学检查结果不明显时,才能做出“生理性蛋白尿”的诊断。在缺乏肾脏组织学检查的情况下,每种形式的蛋白尿起初都应归因于肾小球病变。