Law S P
Acta Obstet Gynecol Scand. 1986;65(1):45-8. doi: 10.3109/00016348609158228.
A synchronous relationship between the menstrual cycle and lunar rhythm was confirmed by: Investigative data: Among the 826 female volunteers with a normal menstrual cycle, aged between 16 and 25 years, a large proportion of menstruations occurred around the new moon (28.3%), while at other times during the lunar month the proportion of menstruations occurring ranged between 8.5-12.6%; the difference was significant (p less than 0.01).
The 6-hydroxymelatonin levels in the urina sanguinis of 3 female volunteers reached their zenith prior to and during menstruation, gradually declining to their nadir during ovulation. The difference in 6-hydroxymelatonin between menstruation and ovulation was significant (p less than 0.01). Two of these three volunteers had their zenith in the period of the new moon and nadir 3-4 days prior to the full moon respectively. Clinical experience: The lunar-menses-regulatory therapy in treatment of Nephropenic secondary amenorrhea revealed 4 clinical cure, 5 marked effect, 8 menogogue and 3 ineffect out of 20 cases.
月经周期与月节律之间的同步关系通过以下方式得到证实：调查数据：在826名月经周期正常、年龄在16至25岁之间的女性志愿者中，很大一部分月经发生在新月前后（28.3%），而在农历月的其他时间，月经发生的比例在8.5%至12.6%之间；差异具有统计学意义（p小于0.01）。
3名女性志愿者血尿中6-羟基褪黑素水平在月经前及月经期间达到峰值，在排卵期间逐渐降至最低点。月经与排卵期间6-羟基褪黑素的差异具有统计学意义（p小于0.01）。这三名志愿者中有两名分别在新月期达到峰值，在满月前3至4天降至最低点。临床经验：在治疗肾性继发性闭经的月-经调节疗法中，20例中有4例临床治愈，5例显效，8例有催经作用，3例无效。
