Judy Wesley C, Griffith Elliot, Palomo Pablo, Denham Jolanda M, Douglas-Lindsay Dorothea, Shao Lei, Cadilla Adriana, Donnelly Margaret, Franciosi James P
From the Division of General Pediatrics, Nemours Children's Hospital, Orlando, FL.
Division of Gastroenterology, Hepatology and Nutrition, Nemours Children's Hospital, Orlando, FL.
JPGN Rep. 2022 Oct 20;3(4):e252. doi: 10.1097/PG9.0000000000000252. eCollection 2022 Nov.
Kaposi sarcoma (KS) of the gastrointestinal (GI) tract in a patient with acquired immunodeficiency syndrome (AIDS) has not been reported in an adolescent outside of Africa. We present a 16-year homosexual old male with AIDS, cutaneous KS, pulmonary KS, and gastrointestinal KS (GI-KS) lesions. Eighty percent of patients with GI-KS are asymptomatic, but our patient presented with a month-long history of dysphagia, abdominal pain, and hematochezia. Endoscopy with biopsies revealed multiple KS lesions within the stomach and lower GI tract. This novel case demonstrates the importance of considering early endoscopic screening in immunocompromised adolescents with cutaneous KS to improve morbidity and mortality.
在非洲以外地区，青少年获得性免疫缺陷综合征（AIDS）患者发生胃肠道（GI）卡波西肉瘤（KS）的情况尚未见报道。我们报告了一名16岁的同性恋男性AIDS患者，其患有皮肤KS、肺部KS和胃肠道KS（GI-KS）病变。80%的GI-KS患者无症状，但我们的患者有长达一个月的吞咽困难、腹痛和便血病史。内镜检查及活检显示胃和下消化道内有多个KS病变。这个新病例表明，对于患有皮肤KS的免疫功能低下青少年，考虑早期内镜筛查以改善发病率和死亡率具有重要意义。
