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肛周外阴 Paget 病患者的光动力疗法。

Photodynamic therapy in a patient with perianal extramammary Paget's disease.

机构信息

P.A. Hertsen Moscow Oncology Research Center - Branch of Federal State Budgetary Institution National Medical Research Radiological Center of the Ministry of Health of the Russian Federation, Moscow, Russia.

P.A. Hertsen Moscow Oncology Research Center - Branch of Federal State Budgetary Institution National Medical Research Radiological Center of the Ministry of Health of the Russian Federation, Moscow, Russia; Peoples' Friendship University of Russia (RUDN University), Moscow, Russia.

出版信息

Photodiagnosis Photodyn Ther. 2023 Jun;42:103603. doi: 10.1016/j.pdpdt.2023.103603. Epub 2023 May 9.

DOI:10.1016/j.pdpdt.2023.103603
PMID:37169171
Abstract

Extramammary Paget's disease is a rare neoplasm of apocrine gland-bearing areas of the skin. One of the most common localizations of such a tumor is the perianal area. Surgery is the most frequently reported therapy. However, it is an invasive procedure and complicated by a high recurrence rate. An alternative to surgical treatment may be non-invasive photodynamic therapy. We describe in this article the case of a 69-year-old patient with extramammary Paget's disease (a large tumor in the perianal area 22 × 18 cm) successfully treated with chlorin e6 photodynamic therapy.

摘要

派杰氏病是一种罕见的皮肤顶泌汗腺肿瘤。这种肿瘤最常见的部位之一是肛门周围区域。手术是最常报道的治疗方法。然而,手术是一种有创性的治疗方法,其复发率很高。手术治疗的替代方法可能是无创的光动力疗法。我们在本文中描述了一位 69 岁的患者,该患者患有派杰氏病(肛门周围区域有一个 22×18cm 的大肿瘤),成功地接受了氯乙六环素光动力疗法治疗。

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