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对比经胸主动脉腔内修复术治疗的 B 型主动脉夹层和主动脉壁内血肿患者的人口统计学特征和临床结局:倾向评分匹配分析。

Comparison of population characteristics and clinical outcomes of patients with type B aortic dissection or aortic intramural hematoma underwent thoracic endovascular aortic repair: a propensity score-matched analysis.

机构信息

Department of Cardiology and Cardiovascular Research Institute, General Hospital of Northern Theater Command, Shenyang, 110016, Liaoning, China.

China Medical University, Shenyang, 110122, Liaoning, China.

出版信息

J Cardiothorac Surg. 2023 May 11;18(1):180. doi: 10.1186/s13019-023-02280-8.

Abstract

BACKGROUNDS

Survival and aortic-related adverse events after thoracic endovascular aortic repair (TEVAR) for aortic intramural hematoma (IMH) and aortic dissection (AD) are controversial. We aimed to assess the preoperative characteristics and to evaluate TEVAR outcomes of acute type B IMH and AD.

METHODS

Between June 2002 and May 2021, 83 patients with acute type B IMH and 755 patients with acute type B AD underwent TEVAR at the General Hospital of Northern Theater Command. We retrospectively analyzed data from these patients, including clinical characteristics and follow-up outcomes.

RESULTS

The patients with IMH were significantly older than the ones with AD (P < 0.001). Diabetes mellitus (P = 0.035) and ischemic cerebrovascular disease (P = 0.017) were more common in the IMH group than in the AD group. The results demonstrated a less long-term aortic-related death-free survival rate in the IMH group than the AD group for all the patients (P = 0.014) and the matched patients (P = 0.027). It also presents a lower long-term overall survival rate (P = 0.047) and aortic-related event-free rate (P = 0.048) in the IMH group than in the matched patients.

CONCLUSIONS

Compared with AD patients, patients with IMH who underwent TEVAR had a worse long-term outcome of aortic-related survival in all and matched patients.

摘要

背景

胸主动脉腔内修复术(TEVAR)治疗主动脉壁内血肿(IMH)和主动脉夹层(AD)的生存和主动脉相关不良事件仍存在争议。本研究旨在评估急性 B 型 IMH 和 AD 的术前特征,并评估 TEVAR 的结果。

方法

2002 年 6 月至 2021 年 5 月,在北部战区总医院接受 TEVAR 治疗的 83 例急性 B 型 IMH 患者和 755 例急性 B 型 AD 患者,回顾性分析这些患者的临床特征和随访结果。

结果

IMH 组患者明显比 AD 组患者年龄大(P<0.001)。IMH 组比 AD 组更常见糖尿病(P=0.035)和缺血性脑血管病(P=0.017)。结果表明,所有患者(P=0.014)和匹配患者(P=0.027)中,IMH 组的长期主动脉相关无死亡生存率均低于 AD 组。IMH 组的长期总生存率(P=0.047)和主动脉相关无事件生存率(P=0.048)均低于匹配患者。

结论

与 AD 患者相比,接受 TEVAR 治疗的 IMH 患者在所有患者和匹配患者中均具有较差的长期主动脉相关生存结局。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1533/10176865/8760345f8647/13019_2023_2280_Fig1_HTML.jpg

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