Contact Lens and Visual Optics Laboratory, School of Optometry and Vision Science, Centre for Vision and Eye Research, Queensland University of Technology, Brisbane, Queensland, Australia.
Ophthalmic Physiol Opt. 2023 Sep;43(5):1065-1069. doi: 10.1111/opo.13161. Epub 2023 May 11.
One clinical approach to address poor front surface wettability during scleral lens wear is the use of a "reverse piggyback" system (a soft contact lens applied to the anterior surface of a scleral lens). The aim of this study was to compare the magnitude of corneal oedema induced following short-term reverse piggyback scleral lens wear and standard scleral lens wear.
Ten young (mean age 22 ± 6 years) healthy participants with normal corneas were recruited. On separate days, central corneal thickness and fluid reservoir thickness were measured using optical coherence tomography before and after 90 min of standard scleral lens wear (Kerectasia Alignment Tangent Torus diagnostic lenses, hexafocon A, Dk 100 × 10 (cm /s)(ml O /ml × mmHg), Capricornia Contact Lenses, capcl.com.au) and reverse piggyback scleral lens wear (the same scleral lens with a Dailies Total 1®, delefilcon A, Dk 140 × 10 (cm /s)(ml O /ml × mmHg), Alcon, alcon.com, applied to the anterior scleral lens surface).
After correcting for small variations in the initial central fluid reservoir thickness, central corneal oedema was similar between the reverse piggyback (2.32 ± 1.15%) and standard scleral lens conditions (2.02 ± 0.76%; p = 0.45).
Following 90 min of lens wear, the highly oxygen-permeable reverse piggyback system did not induce a clinically or statistically greater magnitude of central corneal oedema compared with standard scleral lens wear in young adults with healthy corneas. This approach may be suitable to address poor front surface scleral lens wettability or to correct residual refractive error during diagnostic scleral lens fitting.
解决巩膜镜佩戴时前表面润湿性差的一种临床方法是使用“反向覆盖”系统(将软镜应用于巩膜镜的前表面)。本研究旨在比较短期反向覆盖巩膜镜佩戴和标准巩膜镜佩戴后角膜水肿的程度。
招募了 10 名年轻(平均年龄 22 ± 6 岁)健康正常角膜的参与者。在不同的日子里,使用光学相干断层扫描在佩戴标准巩膜镜(Kerectasia Alignment Tangent Torus 诊断镜片,六氟烷 A,Dk100×10(cm/s)(ml O/ml×mmHg),Capricornia Contact Lenses,capcl.com.au)和反向覆盖巩膜镜(相同的巩膜镜与 Dailies Total 1®,delefilcon A,Dk140×10(cm/s)(ml O/ml×mmHg),Alcon,alcon.com 应用于前巩膜镜表面)前和 90 分钟后测量中央角膜厚度和流体储层厚度。
在对初始中央流体储层厚度的微小变化进行校正后,反向覆盖(2.32±1.15%)和标准巩膜镜条件(2.02±0.76%;p=0.45)之间的中央角膜水肿相似。
在佩戴镜片 90 分钟后,高度透氧的反向覆盖系统在年轻健康角膜的成年人中,与标准巩膜镜佩戴相比,并未引起中央角膜水肿的临床或统计学上更大程度的增加。这种方法可能适用于解决巩膜镜前表面润湿性差的问题,或在诊断性巩膜镜适配过程中纠正残留的屈光误差。