Department of Vascular Surgery, General Surgery Center, The First Hospital of Jilin University, Changchun, China.
Medicine (Baltimore). 2023 May 12;102(19):e33764. doi: 10.1097/MD.0000000000033764.
Brucellosis is one of the most common zoonotic diseases in the world. Although cardiovascular complications of human brucellosis account for only 3% of morbidity, they are the leading cause of death. Peripheral vascular disease due to brucellosis is rare and under-reported in the literature.
Two patients with previous brucellosis, both of whom had been treated with anti-brucellosis, were admitted to vascular surgery for thoracic aortic ulcer and abdominal aortic pseudoaneurysm, respectively, with positive IgG antibody to brucellosis and negative IgM antibody to brucellosis, tube agglutination test, and blood culture. These 2 patients were successfully treated with aortic stent-graft implantation and followed up for 8 and 10 weeks without complications.
Chronic damage to human blood vessels by brucellosis may not disappear with brucellosis treatment, and peripheral blood vessels should be examined annually in people previously diagnosed with brucellosis. Clinicians in related departments should pay attention to peripheral vascular complications of brucellosis.
布鲁氏菌病是世界上最常见的人畜共患疾病之一。尽管人类布鲁氏菌病的心血管并发症仅占发病率的 3%,但却是主要的致死原因。文献中鲜有布鲁氏菌病引起的外周血管疾病的报道。
两名曾患有布鲁氏菌病的患者,均经抗布鲁氏菌治疗,分别因胸主动脉溃疡和腹主动脉假性动脉瘤入血管外科就诊,布鲁氏菌 IgG 抗体阳性,IgM 抗体阴性,试管凝集试验和血培养阳性。这 2 名患者均成功接受了主动脉覆膜支架植入术,随访 8 周和 10 周均无并发症。
布鲁氏菌对人体血管的慢性损害可能不会随着布鲁氏菌病的治疗而消失,曾被诊断为布鲁氏菌病的患者应每年检查外周血管。相关科室的临床医生应注意布鲁氏菌病的外周血管并发症。