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儿童由 Percheron 动脉供血的中脑动静脉畸形的栓塞治疗:首例病例报告及文献复习。

Embolization of midbrain arteriovenous malformation fed by the artery of Percheron in a child, the first case report and literature review.

机构信息

Department of Neurosurgery, Children's Hospital of Chongqing Medical University, National Research Center for Child Health and Disorders, No. 20, Jing Yu Road, Yu Bei District, Chongqing, 400015, People's Republic of China.

出版信息

Childs Nerv Syst. 2023 Sep;39(9):2527-2532. doi: 10.1007/s00381-023-05978-1. Epub 2023 May 12.

Abstract

BACKGROUND

Artery of Percheron (AOP) as main feeder artery of arteriovenous malformation (AVM) is extremely rare. Two cases of thalamic AVM fed by AOP have been reported to date and only one AVM been removed by microsurgery when attempt of intervention embolization failed. Midbrain AVM fed by AOP has not been reported yet.

CASE PRESENTATION

Here, we presented the first successful embolized case of midbrain AVM supplied by the AOP in a 10-year-old boy, who suffered dual oculomotor nerve palsy and secondary hemorrhage before embolization. During endovascular embolization, selective angiography by 1.2 Fr. Magic microcatheter showed an intranidal aneurysm located on the distal AOP. Two injections of a 1:4 ratio mixture of NBCA-MS completely occlude the nidus and intranidal aneurysm with no complications occurred. The child recovered well and the oculomotor deficits improved.

CONCLUSION

This case highlighted that AOP is a clinically significant branch associated with AVM in midbrain and thalamus. Moreover, intervention embolization of midbrain AVM fed by AOP is a considerable therapeutic strategy.

摘要

背景

由 Percheron 动脉(AOP)作为主要供血动脉的动静脉畸形(AVM)极为罕见。迄今为止,已有两例由 AOP 供血的丘脑 AVM 被报道,且当介入栓塞尝试失败时,仅通过显微手术切除了一例 AVM。由 AOP 供血的中脑 AVM 尚未被报道。

病例介绍

在这里,我们报道了首例由 AOP 供血的 10 岁男孩中脑 AVM 成功栓塞的病例,该男孩在栓塞前患有动眼神经和滑车神经双重麻痹和继发性出血。在血管内栓塞过程中,通过 1.2Fr. Magic 微导管进行选择性血管造影显示,位于远端 AOP 的颅内动脉瘤。两次注射 1:4 比例的 NBCA-MS 混合物完全闭塞了病灶和颅内动脉瘤,无并发症发生。患儿恢复良好,动眼神经缺损得到改善。

结论

本病例强调了 AOP 是与中脑和丘脑 AVM 相关的具有临床意义的分支。此外,由 AOP 供血的中脑 AVM 的介入栓塞是一种可行的治疗策略。

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