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健康青年在接受生长激素激发试验时,与生活质量和自尊相关的患者和家长特征。

Patient and Parent Characteristics Related to Quality of Life and Self-Esteem in Healthy Youth Undergoing Provocative Growth Hormone Testing.

机构信息

Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA; Division of Endocrinology and Diabetes, Children's Hospital of Philadelphia, Philadelphia, PA.

Craig Dalsimer Division of Adolescent Medicine, Children's Hospital of Philadelphia, Philadelphia, PA.

出版信息

J Pediatr. 2023 Sep;260:113460. doi: 10.1016/j.jpeds.2023.113460. Epub 2023 May 11.

DOI:10.1016/j.jpeds.2023.113460
PMID:37172805
Abstract

OBJECTIVE

To examine how height and youth as well as parenting characteristics associate with quality of life (QoL) and self-esteem among healthy youth undergoing growth evaluation with growth hormone (GH) testing.

STUDY DESIGN

Healthy youth, aged 8-14 years, undergoing provocative GH testing, and a parent completed surveys at or around the time of testing. Surveys collected demographic data; youth and parent reports of youth health-related QoL; youth reports of self-esteem, coping skills, social support, and parental autonomy support; and parent reports of perceived environmental threats and achievement goals for their child. Clinical data were extracted from electronic health records. Univariate models and multivariable linear regressions were used to identify factors associated with QoL and self-esteem.

RESULTS

Sixty youth (mean height z score -2.18 ± 0.61) and their parents participated. On multivariable modeling, youth perceptions of their physical QoL associated with higher grade in school, greater friend and classmate support, and older parent age; youth psychosocial QoL with greater friend and classmate support, and with less disengaged coping; and youth height-related QoL and parental perceptions of youth psychosocial QoL with greater classmate support. Youth self-esteem associated with greater classmate support and taller mid-parental height. Youth height was not associated with QoL or self-esteem outcomes in multivariable regression.

CONCLUSIONS

Perceived social support and coping skills, rather than height, were related to QoL and self-esteem in healthy short youth and may serve as an important potential area for clinical intervention.

摘要

目的

研究身高、年轻程度以及养育特征如何与接受生长激素(GH)检测的健康生长评估青少年的生活质量(QoL)和自尊相关。

研究设计

健康的 8-14 岁青少年在接受激发性 GH 检测时,他们本人及其父母会同时完成调查。调查收集了人口统计学数据;青少年及其父母对青少年健康相关 QoL 的报告;青少年对自尊、应对技能、社会支持和父母自主支持的报告;以及父母对感知环境威胁和对孩子的成就目标的报告。临床数据从电子健康记录中提取。使用单变量模型和多变量线性回归来确定与 QoL 和自尊相关的因素。

结果

60 名青少年(平均身高 z 评分-2.18±0.61)及其父母参与了研究。在多变量模型中,青少年对身体 QoL 的感知与较高的年级、更多的朋友和同学支持以及父母年龄较大有关;青少年的心理社会 QoL 与更多的朋友和同学支持以及较少的不参与应对方式有关;青少年的身高相关 QoL 和父母对青少年心理社会 QoL 的感知与更多的同学支持有关。青少年的自尊与更多的同学支持和更高的父母平均身高有关。在多变量回归中,青少年的身高与 QoL 或自尊结果无关。

结论

在健康的矮个青少年中,与 QoL 和自尊相关的是感知到的社会支持和应对技能,而不是身高,这可能是临床干预的一个重要潜在领域。

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Horm Res Paediatr. 2021;94(9-10):353-363. doi: 10.1159/000520250. Epub 2021 Oct 18.
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Impact of short stature on quality of life: A systematic literature review.矮小身材对生活质量的影响:系统文献回顾。
Growth Horm IGF Res. 2021 Apr-Jun;57-58:101392. doi: 10.1016/j.ghir.2021.101392. Epub 2021 Apr 30.
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Racial and Ethnic Disparities in the Investigation and Treatment of Growth Hormone Deficiency.
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