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辐射对产前发育的影响及其放射学意义。

Radiation effects on pre-natal development and their radiological significance.

作者信息

Mole R H

出版信息

Br J Radiol. 1979 Feb;52(614):89-101. doi: 10.1259/0007-1285-52-614-89.

Abstract

The evidence relating to pre-natal radiation exposure and the subsequent occurrence of malformations and cancer suggests that the overall risk lies in the range 0--1 cases per 1000 irradiated by one rad in utero in the first four months of pregnancy. The natural level of occurrence of serious handicaps in average pregnancies is at least 30 times higher. Is the much lower probability of radiation-induced harm sufficiently high to justify (a) concern when a woman who has been irradiated is found to have been pregnant at that time, or (b) the maintenance of restrictions on medical uses of ionizing radiation in women in the reproductive age, such as the ten day rule?

摘要

关于产前辐射暴露与随后出现畸形和癌症的证据表明,总体风险处于每1000名在孕期头四个月接受1拉德宫内照射的胎儿中有0至1例的范围内。普通妊娠中严重残疾的自然发生率至少要高30倍。辐射诱发伤害的概率要低得多,那么这种概率是否足够高,足以证明:(a) 当发现接受过辐射的女性当时已怀孕时,是否应予以关注;或 (b) 是否应维持对育龄女性电离辐射医疗用途的限制,例如十天规则?

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