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辐射对产前发育的影响及其放射学意义。

Radiation effects on pre-natal development and their radiological significance.

作者信息

Mole R H

出版信息

Br J Radiol. 1979 Feb;52(614):89-101. doi: 10.1259/0007-1285-52-614-89.

DOI:10.1259/0007-1285-52-614-89
PMID:371736
Abstract

The evidence relating to pre-natal radiation exposure and the subsequent occurrence of malformations and cancer suggests that the overall risk lies in the range 0--1 cases per 1000 irradiated by one rad in utero in the first four months of pregnancy. The natural level of occurrence of serious handicaps in average pregnancies is at least 30 times higher. Is the much lower probability of radiation-induced harm sufficiently high to justify (a) concern when a woman who has been irradiated is found to have been pregnant at that time, or (b) the maintenance of restrictions on medical uses of ionizing radiation in women in the reproductive age, such as the ten day rule?

摘要

关于产前辐射暴露与随后出现畸形和癌症的证据表明,总体风险处于每1000名在孕期头四个月接受1拉德宫内照射的胎儿中有0至1例的范围内。普通妊娠中严重残疾的自然发生率至少要高30倍。辐射诱发伤害的概率要低得多,那么这种概率是否足够高,足以证明:(a) 当发现接受过辐射的女性当时已怀孕时,是否应予以关注;或 (b) 是否应维持对育龄女性电离辐射医疗用途的限制,例如十天规则?

相似文献

1
Radiation effects on pre-natal development and their radiological significance.辐射对产前发育的影响及其放射学意义。
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2
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引用本文的文献

1
Pregnancy outcome of women in the vicinity of nuclear power plants in Taiwan.台湾核电站周边地区女性的妊娠结局。
Radiat Environ Biophys. 2010 Mar;49(1):57-65. doi: 10.1007/s00411-009-0246-8. Epub 2009 Oct 16.
2
Congenital abnormalities in children with cancer and their relatives: results from a case-control study (IRESCC).癌症患儿及其亲属的先天性异常:一项病例对照研究(IRESCC)的结果
Br J Cancer. 1993 Aug;68(2):357-63. doi: 10.1038/bjc.1993.340.
3
Diagnostic radiation risks.诊断性辐射风险。
Arch Dis Child. 1980 Apr;55(4):249-51. doi: 10.1136/adc.55.4.249.
4
Patients and radiation--an assessment of the risks.患者与辐射——风险评估
J R Coll Gen Pract. 1984 May;34(262):296-7.
5
Radiation embryology.
Experientia. 1989 Jan 15;45(1):69-77. doi: 10.1007/BF01990454.
6
Occupational exposure and defects of the central nervous system in offspring: review.职业暴露与后代中枢神经系统缺陷:综述
Br J Ind Med. 1990 Sep;47(9):580-8. doi: 10.1136/oem.47.9.580.
7
Radiation and the embryo.辐射与胚胎
Br Med J. 1979 May 26;1(6175):1380-1.