Ferguson Melissa A, Akyalcin Sercan, Campos Hugo, Gliksten Abigail, Hargett Kadriye, Yang Stephanie, MacLaine James
Developmental Biology, Harvard School of Dental Medicine, Boston, MA 02115, USA.
Evidence-Based Health Care Program, University of Oxford, Oxford OX1 3PJ, UK.
Diagnostics (Basel). 2023 May 6;13(9):1642. doi: 10.3390/diagnostics13091642.
In children born with cleft lip and palate, the timing of the secondary alveolar bone graft (SABG) is crucial to its success; this involves estimating the eruption of the permanent maxillary canine. Altered dental eruption in this patient group gives impetus to the identification of dental developmental factors concerning maxillary canine eruption, which may steer the clinical decision of SABG timing. Records of over nine hundred patients who received SABG with pre- and post-operative cone beam computed tomography (CBCT) scans were analyzed for inclusion and divided into two groups (erupting or non-erupting canine after SABG). Roots of the maxillary canines and premolars were segmented from the cementoenamel junction then linear and volumetric measurements were performed. The pre- and post-operative root length and volume differences were calculated and compared statistically using independent sample tests and paired -tests. No statistically significant differences were found in the volume change (%), or reciprocal of mean root length in the erupted and unerupted groups in the canine, first premolar, or second premolar roots except for an association between the post-operative dental root length of the canine and the maxillary canine eruption status. Therefore, assessment of root development from pre-treatment CBCT scans was not deemed worthy from a diagnostic perspective.
对于唇腭裂患儿,二期牙槽骨植骨(SABG)的时机对其成功与否至关重要;这涉及对上颌恒尖牙萌出时间的预估。该患者群体中牙齿萌出的改变促使人们去识别与上颌尖牙萌出有关的牙齿发育因素,这可能会指导SABG时机的临床决策。分析了九百多名接受SABG并进行术前和术后锥形束计算机断层扫描(CBCT)的患者记录以纳入研究,并将其分为两组(SABG后尖牙萌出或未萌出)。从上颌尖牙和前磨牙的牙釉质牙骨质界处分割出牙根,然后进行线性和体积测量。计算术前和术后牙根长度及体积差异,并使用独立样本检验和配对检验进行统计学比较。除了犬齿术后牙根长度与上颌尖牙萌出状态之间存在关联外,在萌出和未萌出组的犬齿、第一前磨牙或第二前磨牙牙根的体积变化(%)或平均牙根长度的倒数方面,未发现统计学上的显著差异。因此,从诊断角度来看,术前CBCT扫描评估牙根发育并不值得。