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[一名41岁女性的恶性高热]

[Malignant hyperthermia in a 41-year-old woman].

作者信息

Popp M, Seeling W

出版信息

Anaesthesist. 1986 Mar;35(3):203-5.

PMID:3717538
Abstract

Malignant hyperthermia is one of the most devastating crises encountered in anaesthesia and it frequently occurs unexpectedly. Although malignant hyperthermia develops in young individuals (mean age approximately 22 years), older people can also be affected. The case of a 41-year-old woman with a history of several previously uneventful general anaesthetics is described. She developed the complete symptomatology of malignant hyperthermia triggered by halothane anaesthesia, with tachycardia, cardiac arrhythmia, cyanosis, combined respiratory and metabolic acidosis and hyperpyrexia. Because treatment with dantrolene and hyperventilation with 100% O2 was started immediately, the symptoms of malignant hyperthermia were stopped within a short time. It should always be remembered, that the life threatening crises which can be caused by malignant hyperthermia can occur at any age and even after several uneventful anaesthetics.

摘要

恶性高热是麻醉中遇到的最具破坏性的危机之一,且常常意外发生。虽然恶性高热多发生于年轻人(平均年龄约22岁),但老年人也可能受到影响。本文描述了一名41岁女性的病例,她既往曾接受过几次平安无事的全身麻醉。她在接受氟烷麻醉后出现了恶性高热的全部症状,包括心动过速、心律失常、发绀、呼吸性和代谢性酸中毒合并以及高热。由于立即开始使用丹曲林治疗并进行100%氧气过度通气,恶性高热的症状在短时间内得到了控制。应当始终牢记,恶性高热可能引发的危及生命的危机可发生于任何年龄,甚至在几次平安无事的麻醉之后。

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