Chen Tongshuai, Chang Lujie, Rong Bing, Zhang Kai, Fan Guanqi, Kong Jing, Ling Mingying, Kong Qingyu, Maduray Kellina, Zhao Cuifen, Zhong Jingquan
National Key Laboratory for Innovation and Transformation of Luobing Theory, The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, Department of Cardiology, Qilu Hospital of Shandong University, Jinan 250012, China.
Department of Pediatric Cardiology, Qilu Hospital of Shandong University, Jinan 250012, China.
J Clin Med. 2023 Apr 27;12(9):3154. doi: 10.3390/jcm12093154.
The catheter ablation of ventricular arrhythmias (VAs) arising from the left ventricular (LV) papillary muscles (PMs) is challenging. This study sought to address whether the combination of intracardiac echocardiography (ICE) and contact force sensing (CFS) can improve the acute and long-term ablation outcomes of left ventricular papillary muscle arrhythmias.
From May 2015 to August 2022, a total of thirty-three patients underwent catheter ablation for LV PM arrhythmias: VAs were located in anterolateral PMs in 11 and posteromedial PMs in 22. A combination of intracardiac echocardiography (ICE) and contact force sensing (CFS) was used in 21 of the 33 procedures. A mean of 6.93 ± 4.91 for lesions was used per patient, comparable between the CFS/ICE and no ICE/CFS (4.90 ± 2.23 vs. 10.17 ± 5.89; = 0.011). The mean CF achieved in the ICE/CFS group was 7.52 ± 3.31 g. Less X-ray time was used in the combination group (CFS/ICE: 165.67 ± 47.80 S vs. no ICE/CFS: 365.00 ± 183.73 S; < 0.001). An acute success rate of 100% was achieved for the ICE/CFS group (n = 22) and 66.67% for the no ICE/CFS group (n = 8). VA recurrence at the 11.21 ± 7.21-month follow-up was 14.2% for the ICE/CFS group and 50% for the no ICE/CFS group ( = 0.04). No severe complications occurred in all patients.
The combination of intracardiac echocardiography (ICE) and contact force sensing (CFS) could provide precise geometries of cardiac endocavitary structures and accurate contact information for the catheter during ablation, which improved acute and long-term ablation outcomes. The routine adoption of this strategy should be considered to improve the outcomes of LV PM VA ablation.
对起源于左心室(LV)乳头肌(PMs)的室性心律失常(VAs)进行导管消融具有挑战性。本研究旨在探讨心腔内超声心动图(ICE)和接触力传感(CFS)相结合是否能改善左心室乳头肌心律失常的急性和长期消融效果。
2015年5月至2022年8月,共有33例患者接受了左心室乳头肌心律失常的导管消融:室性心律失常位于前外侧乳头肌11例,后内侧乳头肌22例。33例手术中有21例采用了心腔内超声心动图(ICE)和接触力传感(CFS)相结合的方法。每位患者平均使用6.93±4.91个消融灶,CFS/ICE组和非ICE/CFS组相当(4.90±2.23 vs. 10.17±5.89;P = 0.011)。ICE/CFS组达到的平均接触力为7.52±3.31克。联合组使用的X线时间更少(CFS/ICE:165.67±47.80秒 vs. 非ICE/CFS:365.00±183.73秒;P < 0.001)。ICE/CFS组(n = 22)急性成功率为100%,非ICE/CFS组(n = 8)为66.67%。在11.21±7.21个月的随访中,ICE/CFS组室性心律失常复发率为14.2%,非ICE/CFS组为50%(P = <0.04)。所有患者均未发生严重并发症。
心腔内超声心动图(ICE)和接触力传感(CFS)相结合可在消融过程中提供心脏腔内结构的精确几何形状和导管的准确接触信息,从而改善急性和长期消融效果。应考虑常规采用该策略以改善左心室乳头肌室性心律失常消融的效果。