Jones R C, Singer A C, Edgren R A
Int J Fertil. 1979;24(1):39-43.
The dextrorotatory enantiomer of norgestrel has now been tested by oral and parenteral routes in a broad range of biological assays and its inactivity has been confirmed. The active enantiomer has been further compared with the racemate in a similarly broad range of tests, largely by the oral route. Levonorgestrel was twice as potent as the racemate in experiments in which norgestrel was effective. These data reinforce earlier findings that levonorgestrel is responsible for all the biological activity found in norgestrel.
炔诺孕酮的右旋对映体现已通过口服和非肠道途径在广泛的生物学试验中进行了测试，其无活性已得到证实。活性对映体已在同样广泛的试验中，主要通过口服途径，与消旋体作了进一步比较。在炔诺孕酮有效的实验中，左炔诺孕酮的效力是消旋体的两倍。这些数据强化了早期的研究结果，即左炔诺孕酮是炔诺孕酮中所有生物学活性的原因。
