Selçuk University, Health Science Faculty, Department of Audiology, Turkey.
Turkish Ministry of Health, Eskişehir City Hospital, Eskişehir, Turkey.
Int J Pediatr Otorhinolaryngol. 2023 Jul;170:111597. doi: 10.1016/j.ijporl.2023.111597. Epub 2023 May 8.
Auditory Brainstem Response (ABR), the electrical responses in the neuronal pathways extending from the inner ear to the auditory cortex, are evaluated with auditory stimuli. ABR analysis evaluates waves I, III and V's absolute-latencies, amplitude values, interpeak-latencies, interaural-latency differences, and morphologies. This study aims to reveal the advantages of CE-Chirp® LS stimulus and its clinical uses to increase by comparing the amplitude, latency, and interpeak-latency differences of waves I, III, and V at 80 dB nHL and wave V at 60, 40, 20 dB nHL by using click and CE-Chirp® LS stimuli.
100 (54 boys, 46 girls) infants with normal hearing were included in the National Newborn Hearing Screening Program. With the click and CE-Chirp® LS ABR, the absolute latency and amplitude values of wave V at 20, 40, and 60 dB nHL, and the absolute-latency, interpeak-latency, and amplitude values of waves I, III, and V at 80 dB nHL are determined between stimuli and right-left ear.
When the wave V latency and amplitudes obtained at 80, 60, 40, and 20 dB nHL levels were examined between genders, and according to the risk factor, no significant difference was found between click and CE-Chirp® LS stimuli (p > 0.05). Waves I, III, and V absolute-latency, amplitudes were compared at 80 dB nHL and wave V absolute-latency, amplitudes at 60, 40, and 20 dB nHL; the amplitudes measured with CE-Chirp® LS were significantly higher than the click stimulus (p < 0.05). When two stimuli were compared for I-III and III-V interpeak-latency values at 80 dB nHL level, no significant difference was found between the two stimuli (p > 0.05). However, the I-V interpeak-latency value was statistically significantly decreased for two stimuli, regardless of the ear (p < 0.05).
It is suggested to increase the use of CE-Chirp® LS stimulus with better morphology and amplitude in clinics, believing that it facilitates clinicians' interpretation.
听觉脑干反应（ABR）是评估从内耳到听觉皮层的神经元通路的电反应，使用听觉刺激进行评估。ABR 分析评估波 I、III 和 V 的绝对潜伏期、振幅值、峰间潜伏期、耳间潜伏期差异和形态。本研究旨在通过比较使用 click 和 CE-Chirp® LS 刺激时波 I、III 和 V 在 80 dB nHL 时的波 V 的振幅、潜伏期和峰间潜伏期差异，以及波 V 在 60、40 和 20 dB nHL 时的振幅，来揭示 CE-Chirp® LS 刺激的优势及其临床应用。
100 名（54 名男孩，46 名女孩）听力正常的婴儿参加了全国新生儿听力筛查计划。使用 click 和 CE-Chirp® LS ABR，在刺激左右耳时，确定波 V 在 20、40 和 60 dB nHL 时的绝对潜伏期和振幅值，以及波 I、III 和 V 在 80 dB nHL 时的绝对潜伏期、峰间潜伏期和振幅值。
当比较 80、60、40 和 20 dB nHL 水平时性别之间获得的波 V 潜伏期和振幅，以及根据风险因素，click 和 CE-Chirp® LS 刺激之间没有发现显著差异（p > 0.05）。比较 80 dB nHL 时的波 I、III 和 V 绝对潜伏期和振幅，以及波 V 在 60、40 和 20 dB nHL 时的绝对潜伏期和振幅；CE-Chirp® LS 测量的振幅明显高于 click 刺激（p < 0.05）。当比较 80 dB nHL 水平时的 I-III 和 III-V 峰间潜伏期值时，两种刺激之间没有发现显著差异（p > 0.05）。然而，无论耳朵如何，两种刺激都使 I-V 峰间潜伏期值显著降低（p < 0.05）。
建议在临床上更多地使用 CE-Chirp® LS 刺激，因其具有更好的形态和振幅，有助于临床医生的解释。
