Palladium Nanoparticle-Decorated Porous Metal-Organic-Framework (Zr)@Guanidine: Novel Efficient Catalyst in Cross-Coupling (Suzuki, Heck, and Sonogashira) Reactions and Carbonylative Sonogashira under Mild Conditions.

A novel heterogeneous Zr-based metal-organic framework containing an amino group functionalized with nitrogen-rich organic ligand (guanidine), through a step-by-step post synthesis modification approach, was successfully modified by the stabilization of palladium metal nanoparticles on the prepared UiO-66-NH support in order to synthesize the Suzuki-Murray, Mizoroki-Heck, and copper-free Sonogashira reactions and also the carbonylative Sonogashira reaction incorporating HO as a green solvent under mild conditions. This newly synthesized highly efficient and reusable UiO-66-NH@cyanuric chloride@guanidine/Pd-NPs reported catalyst has been utilized to increase anchoring palladium onto the substrate with the aim of altering the construction of the intended synthesis catalyst to form the C-C coupling derivatives. Several strategies, including X-ray diffraction, Fourier transform infrared, scanning electron microscopy, Brunauer-Emmett-Teller, transmission microscopy electron, thermogravimetric analysis, inductively coupled plasma, energy-dispersive X-ray, and elemental mapping analyzes, were used to indicate the successful preparation of the UiO-66-NH@cyanuric chloride@guanidine/Pd-NPs. In these reactions, the UiO-66-NH-supported Pd-NPs illustrated superior performances compared to their catalyst, revealing the benefits of providing nanocatalysts. As a result, the proposed catalyst is favorable in a green solvent, and also, the outputs are accomplished with good to excellent outputs. Furthermore, the suggested catalyst represented very good reusability with no remarkable loss in activity up nine sequential runs.