Preparation of gold nanoparticles decorated UiO-66-NH incorporated epichlorohydrin and cyclodextrin as novel efficient catalyst in cross coupling and carbonylative reactions.

This study presents a new, highly effective, and reusable catalyst: UiO-66-NH@Epichlorohydrin@Cyclodextrin@Au-NPs. This innovative catalyst starts with the Zr-based UiO-66 material, which is functionalized with amino groups (-NH). We enhanced its surface compatibility by modifying it with epichlorohydrin and cyclodextrin via a post-synthesis modification method. Gold nanoparticles were then stabilized on this modified composite, resulting in the UiO-66-NH@Epichlorohydrin@Cyclodextrin@Au-NPs complex. We used this catalyst for C-C coupling and Carbonylative Sonogashira reactions in mild conditions. Its effectiveness was underscored by various analytical techniques, including XRD, EDS, SEM, FT-IR, TEM, BET, ICP, TGA, and elemental mapping. The catalyst exhibited exceptional performance in Sonogashira, Heck, Suzuki coupling, and Carbonylative reactions, achieving good to excellent yields. It proved to be highly recyclable, maintaining its catalytic activity for up to nine cycles with minimal loss.