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甲状腺毒症中的生长

Growth in thyrotoxicosis.

作者信息

Buckler J M, Willgerodt H, Keller E

出版信息

Arch Dis Child. 1986 May;61(5):464-71. doi: 10.1136/adc.61.5.464.

DOI:10.1136/adc.61.5.464
PMID:3717992
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1777809/
Abstract

To study the effect of thyrotoxicosis on growth, 46 children and adolescents presenting with thyrotoxicosis have been reviewed and followed up for several years, in most cases until adult height was achieved. At presentation the children were underweight for height but were above expected heights even if already well advanced in puberty. Despite bone ages often being very advanced at diagnosis, the condition had no adverse effect on ultimate stature, which was commonly greater than that expected on the basis of parental height. Wight was rapidly regained on treatment, but nevertheless the younger subjects continued to be underweight despite adequate prolonged control of thyrotoxicosis.

摘要

为研究甲状腺毒症对生长的影响,对46例患有甲状腺毒症的儿童和青少年进行了回顾性研究,并随访数年,多数情况下随访至达到成人身高。就诊时,这些儿童身高对应的体重低于正常水平,但即便青春期已发育至较成熟阶段,其身高仍高于预期。尽管诊断时骨龄往往超前,但该病症对最终身高并无不利影响,其身高通常高于基于父母身高所预期的身高。治疗后体重迅速恢复,但较年轻的患者尽管甲状腺毒症得到了充分且长期的控制,体重仍持续低于正常水平。

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本文引用的文献

1
TREATMENT OF JUVENILE THYROTOXICOSIS.青少年甲状腺毒症的治疗
J Pediatr. 1963 Sep;63:402-7. doi: 10.1016/s0022-3476(63)80427-8.
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Skeletal age changes in puberty.青春期骨骼年龄的变化。
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Standards from birth to maturity for height, weight, height velocity, and weight velocity: British children, 1965. I.1965年英国儿童从出生到成年的身高、体重、身高增长速度和体重增长速度标准。I
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Grave'S's disease, an unusual complication: raised intracranial pressure due to premature fusion of skull sutures.格雷夫斯病,一种罕见的并发症:因颅骨缝过早融合导致颅内压升高。
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6
Catch-up in height and skeletal maturity in children on long-term treatment for hypothyroidism.接受长期甲状腺功能减退治疗儿童的身高追赶与骨骼成熟情况
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Premature craniosynostosis: A common complication of juvenile thyrotoxicosis.
J Pediatr. 1978 Aug;93(2):188-91. doi: 10.1016/s0022-3476(78)80493-4.
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Antithyroid drug therapy for toxic diffuse goiter (Graves disease): thirty years experience in children and adolescents.毒性弥漫性甲状腺肿(格雷夫斯病)的抗甲状腺药物治疗:儿童和青少年30年经验
J Pediatr. 1977 Aug;91(2):313-20. doi: 10.1016/s0022-3476(77)80843-3.