Buckler J M, Willgerodt H, Keller E
Arch Dis Child. 1986 May;61(5):464-71. doi: 10.1136/adc.61.5.464.
To study the effect of thyrotoxicosis on growth, 46 children and adolescents presenting with thyrotoxicosis have been reviewed and followed up for several years, in most cases until adult height was achieved. At presentation the children were underweight for height but were above expected heights even if already well advanced in puberty. Despite bone ages often being very advanced at diagnosis, the condition had no adverse effect on ultimate stature, which was commonly greater than that expected on the basis of parental height. Wight was rapidly regained on treatment, but nevertheless the younger subjects continued to be underweight despite adequate prolonged control of thyrotoxicosis.
为研究甲状腺毒症对生长的影响,对46例患有甲状腺毒症的儿童和青少年进行了回顾性研究,并随访数年,多数情况下随访至达到成人身高。就诊时,这些儿童身高对应的体重低于正常水平,但即便青春期已发育至较成熟阶段,其身高仍高于预期。尽管诊断时骨龄往往超前,但该病症对最终身高并无不利影响,其身高通常高于基于父母身高所预期的身高。治疗后体重迅速恢复,但较年轻的患者尽管甲状腺毒症得到了充分且长期的控制,体重仍持续低于正常水平。