Calhoun P, Feldman P S, Armstrong P, Black W C, Pope T L, Minor G R, Daniel T M
Ann Thorac Surg. 1986 Jun;41(6):592-6. doi: 10.1016/s0003-4975(10)63066-4.
One hundred thirty-two of 397 consecutive percutaneous fine needle aspirations done at the University of Virginia between January, 1979, and December, 1984, for pulmonary lesions showed no evidence of cancer on cytological examination. We reviewed the presenting symptoms, radiographic findings on the day of needle aspiration, and the descriptive cytological terms to determine if it was possible to distinguish benign from malignant disease in these 132 patients. We found a specific benign diagnosis in only 16 (12%) of the 132 patients, and 1 of them ultimately was found to have cancer. In the remaining 116 patients, analysis of age, sex, smoking history, presenting symptoms, radiographic findings at the time of needle aspiration, and cytological terms other than malignancy did not enable distinction of benign from malignant disease as the cause of the radiographic finding. In the group of 132 patients without suggestion of cancer on initial cytological study, 38 (29%) were subsequently found to have a malignant process.
1979年1月至1984年12月期间，在弗吉尼亚大学对397例连续性经皮细针穿刺肺病变进行检查，其中132例在细胞学检查中未发现癌症迹象。我们回顾了这些患者的初始症状、穿刺当天的影像学表现以及描述性细胞学术语，以确定在这132例患者中能否区分良性疾病与恶性疾病。我们发现，在这132例患者中，只有16例（12%）得到了明确的良性诊断，其中1例最终被发现患有癌症。在其余116例患者中，对年龄、性别、吸烟史、初始症状、穿刺时的影像学表现以及除恶性肿瘤外的细胞学术语进行分析，无法区分导致影像学表现的疾病是良性还是恶性。在最初细胞学检查未提示癌症的132例患者中，38例（29%）随后被发现患有恶性病变。
