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A型肉毒杆菌毒素治疗磨牙症患者咬肌厚度变化与紧咬牙习惯之间关系的评估

The Evaluation of the Relationship between Changes in Masseter Muscle Thickness and Tooth Clenching Habits of Bruxism Patients Treated with Botulinum Toxin A.

作者信息

Erdil Deniz, Bagis Nilsun, Eren Hakan, Camgoz Melike, Orhan Kaan

机构信息

Department of Periodontology, Faculty of Dentistry, Ankara University, Ankara, Turkey.

Department of Dentomaxillofacial Radiology, Faculty of Dentistry, Canakkale Onsekiz Mart University, Canakkale, Turkey.

出版信息

J Med Ultrasound. 2022 Aug 18;31(1):22-28. doi: 10.4103/jmu.jmu_51_22. eCollection 2023 Jan-Mar.

DOI:10.4103/jmu.jmu_51_22
PMID:37180633
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10173841/
Abstract

BACKGROUND

Bruxism is defined as recurrent masticatory muscle activity. Although there is not an agreed treatment method for bruxism, the application of botulinum toxin A (BT-A) has become a reliable lately. This study aimed to evaluate the correlation between the changes in masseter muscle thickness and clenching habits in bruxism patients treated with BT-A.

METHODS

Twenty-five patients, 23 females and 2 males, diagnosed with possible sleep bruxism were included in the study. The Fonseca Anamnestic Index was applied to the patients to determine their clenching habits and depression levels both before the treatment, and 6 months after it. The masseter muscle thickness was measured using ultrasonography before the treatment and 3 months and 6 months after the treatment. All the patients were injected with a total of 50 U of BT-A, 25 U to each masseter.

RESULTS

A statistically significant decrease in masseter muscle thickness was observed in the ultrasonography 3 and 6 months after the BT-A treatment. There was a statistically significant decrease in the Fonseca scores, in which the teeth clenching habits of the patients were evaluated 6 months after the treatment. Although there was a decrease in the depression levels of the patients 6 months after the treatment, this difference was not statistically significant.

CONCLUSION

When the results of this study were evaluated, it was seen that the BT-A injections are an effective, safe, and side effect-free method in the treatment of bruxism and masseter hypertrophy.

摘要

背景

磨牙症被定义为反复的咀嚼肌活动。尽管目前尚无公认的磨牙症治疗方法,但肉毒杆菌毒素A(BT-A)的应用近来已成为一种可靠的方法。本研究旨在评估接受BT-A治疗的磨牙症患者咬肌厚度变化与紧咬习惯之间的相关性。

方法

本研究纳入了25例被诊断为可能患有睡眠磨牙症的患者,其中23例女性,2例男性。在治疗前及治疗后6个月,对患者应用丰塞卡记忆指数来确定其紧咬习惯和抑郁水平。在治疗前、治疗后3个月和6个月,使用超声测量咬肌厚度。所有患者均接受了总共50 U的BT-A注射,每侧咬肌注射25 U。

结果

在BT-A治疗后3个月和6个月的超声检查中,观察到咬肌厚度有统计学意义的下降。在治疗后6个月评估患者紧咬习惯的丰塞卡评分有统计学意义的下降。尽管治疗后6个月患者的抑郁水平有所下降,但这种差异无统计学意义。

结论

当评估本研究结果时,发现BT-A注射是治疗磨牙症和咬肌肥大的一种有效、安全且无副作用的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d8d/10173841/5f376b42a3e3/JMU-31-22-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d8d/10173841/5626be4750a6/JMU-31-22-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d8d/10173841/ecad5f1ad694/JMU-31-22-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d8d/10173841/5beabf803690/JMU-31-22-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d8d/10173841/55abc3ead8d6/JMU-31-22-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d8d/10173841/76446ac2f3ab/JMU-31-22-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d8d/10173841/5f376b42a3e3/JMU-31-22-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d8d/10173841/5626be4750a6/JMU-31-22-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d8d/10173841/ecad5f1ad694/JMU-31-22-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d8d/10173841/5beabf803690/JMU-31-22-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d8d/10173841/55abc3ead8d6/JMU-31-22-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d8d/10173841/76446ac2f3ab/JMU-31-22-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d8d/10173841/5f376b42a3e3/JMU-31-22-g006.jpg

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