Zhu Jinyun, Zhang Ning, Ma Qunchao, Jin Luhang, Pan Xiaohong
Department of Cardiology, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Department of Cardiology, the Affiliated Hangzhou First People's Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Front Cardiovasc Med. 2023 Apr 27;10:1103918. doi: 10.3389/fcvm.2023.1103918. eCollection 2023.
Primary cardiac tumors are very rare, and about 20-30% of them are malignant tumors Since early signs of cardiac tumors are non-specific, diagnosis can be challenging. There is a lack of the recommended guidelines or standardized strategies for diagnosis and optimal treatment for this disease. As the definite diagnoses of most tumors are made by pathologic confirmation, biopsied tissue is essential in determining the treatment for patients with cardiac tumors. Recently, intracardiac echocardiography (ICE) has been introduced to assist biopsy procedures of cardiac tumors and it provides high-quality imaging.
Due to its low prevalence and variable presentation, cardiac malignant tumors usually are easily missed. Hereby, we report three cases of patients who presented with non-specific signs of cardiac disorder and was initially suspended diagnosis as lung infection or cancer. Under the guidance of ICE, cardiac biopsies were successfully on cardiac masses, giving critical data for diagnosis and treatment planning. No procedural complications were obtained in our cases. These cases are intended to highlight the clinical value and importance of ICE-guided biopsy of intracardiac mass.
The diagnosis of primary cardiac tumors relies on the histopathological results. In our experience, using ICE for biopsy of an intracardiac mass is an attractive tool to increase diagnostic results and reduce the risk of cardiac complications associated with inadequate targeting of the biopsy catheters.
原发性心脏肿瘤非常罕见，其中约20%-30%为恶性肿瘤。由于心脏肿瘤的早期症状不具有特异性，诊断具有挑战性。目前缺乏针对该疾病诊断和最佳治疗的推荐指南或标准化策略。由于大多数肿瘤的明确诊断是通过病理证实，活检组织对于确定心脏肿瘤患者的治疗至关重要。最近，心腔内超声心动图（ICE）已被引入以辅助心脏肿瘤的活检程序，并提供高质量的成像。
由于心脏恶性肿瘤的发病率低且表现多样，通常容易被漏诊。在此，我们报告三例患者，他们最初表现为心脏疾病的非特异性症状，最初被怀疑诊断为肺部感染或癌症。在ICE的引导下，成功对心脏肿块进行了心脏活检，为诊断和治疗计划提供了关键数据。我们的病例中未出现手术并发症。这些病例旨在强调ICE引导下心腔内肿块活检的临床价值和重要性。
原发性心脏肿瘤的诊断依赖于组织病理学结果。根据我们的经验，使用ICE对心腔内肿块进行活检是一种有吸引力的工具，可提高诊断结果并降低与活检导管靶向不足相关的心脏并发症风险。
