Espersen F, Frimodt-Møller N
Arch Intern Med. 1986 Jun;146(6):1118-21.
Staphylococcus aureus endocarditis cases in Denmark from 1976 to 1981 were reviewed. A total of 119 patients--61 female and 58 male, with a median age of 63 years (range, 1 month to 85 years)--fulfilled the diagnostic criteria. Community-acquired infections were most common (62%), but the frequency of hospital-acquired cases (38%) was greater than in earlier reports. The clinical picture was relatively nonspecific, and 32% of the patients had no heart murmurs initially. In 65 cases (55%), endocarditis was not suspected clinically, and the diagnosis was first obtained at autopsy. The mortality was 71% and correlated with age, hospital-acquired infection, and the presence of heart failure and arterial embolism.
对1976年至1981年丹麦的金黄色葡萄球菌性心内膜炎病例进行了回顾。共有119例患者——61名女性和58名男性，年龄中位数为63岁（范围为1个月至85岁）——符合诊断标准。社区获得性感染最为常见（62%），但医院获得性病例的发生率（38%）高于早期报告。临床表现相对缺乏特异性，32%的患者最初没有心脏杂音。在65例（55%）病例中，临床上未怀疑有心内膜炎，诊断首先是在尸检时获得的。死亡率为71%，与年龄、医院获得性感染以及心力衰竭和动脉栓塞的存在相关。
