Gomase Vrushabh G, Deshmukh Prasad, Lekurwale Vedant Y
Otorhinolaryngology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Otolaryngology and Head and Neck Surgery, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Cureus. 2023 Apr 10;15(4):e37359. doi: 10.7759/cureus.37359. eCollection 2023 Apr.
Obstructive sleep apnea (OSA) is a disorder in which there is repeated collapse of the upper airway when the person is in sleep, which causes oxygen desaturation and interrupted sleep. While asleep, airway blockages and collapse are accompanied by awakenings with or without oxygen desaturation. OSA is a prevalent disorder, especially in people with known risk factors and other illnesses. Pathogenesis is variable, and the risk factors include low chest volume, erratic respiratory regulation, and muscular dysfunction in the upper airway dilators. The high-risk factors include overweight, male sex, aging, adenotonsillar hypertrophy, interruption of the menstrual cycle, preservation of liquids, and smoking. The signs are snoring, drowsiness, and apneas. A sleep history, assessment of symptoms, and physical examination are all part of the screening process for OSA, and the data can help determine which people need to be tested for the condition. The results of the polysomnogram or at-home sleep apnea test assist in determining the presence and severity of OSA. Still, it is seen many times that the accuracy of home sleep apnea tests is significantly less, so one should take an expert opinion for the same. OSA results in systemic hypertension, drowsiness, and driving accidents. It is additionally related to diabetes mellitus, congestive heart failure (CHF), cerebral infarction, and myocardial infarction, but the exact mechanism is not known. The preferred treatment is continuous positive airway pressure with 60-70% adherence. Other management options include reducing weight, therapy of oral appliances, and correcting any anatomical obstruction (narrow pharyngeal airway, adenoid hypertrophy, and mass in the pharynx). OSA indirectly causes headaches just after awakening and daytime sleepiness. However, there are no age boundaries in OSA as it can occur in any age group. Still, more prevalence is seen in individuals of more than 60 years of age.
阻塞性睡眠呼吸暂停(OSA)是一种在人睡眠时上呼吸道反复塌陷的疾病,会导致氧饱和度下降和睡眠中断。睡眠时,气道阻塞和塌陷会伴有觉醒,无论是否伴有氧饱和度下降。OSA是一种常见疾病,尤其在有已知危险因素和其他疾病的人群中。其发病机制多种多样,危险因素包括胸廓容积小、呼吸调节不稳定以及上呼吸道扩张肌的肌肉功能障碍。高危因素包括超重、男性、衰老、腺样体扁桃体肥大、月经周期中断、液体潴留和吸烟。症状包括打鼾、嗜睡和呼吸暂停。睡眠史、症状评估和体格检查都是OSA筛查过程的一部分,这些数据有助于确定哪些人需要进行该疾病的检测。多导睡眠图或家庭睡眠呼吸暂停测试的结果有助于确定OSA的存在和严重程度。然而,多次发现家庭睡眠呼吸暂停测试的准确性明显较低,因此对此应寻求专家意见。OSA会导致全身性高血压、嗜睡和交通事故。它还与糖尿病、充血性心力衰竭(CHF)、脑梗死和心肌梗死有关,但确切机制尚不清楚。首选治疗方法是持续气道正压通气,依从率为60 - 70%。其他治疗选择包括减轻体重、口腔矫治器治疗以及纠正任何解剖学上的阻塞(咽气道狭窄、腺样体肥大和咽部肿物)。OSA在刚醒来后会间接导致头痛和白天嗜睡。然而,OSA没有年龄界限,因为它可发生于任何年龄组。不过,60岁以上人群的患病率更高。