School of Geography, Earth and Environmental Sciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom; Nanomedicine, Drug Delivery & Nanotoxicology (NDDN) Lab, School of Pharmacy, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom.
Brazilian Nanotechnology National Laboratory (LNNano), Brazilian Centre for Research in Energy and Materials (CNPEM), Campinas, 13083-100, SP, Brazil; Centre of Nuclear Energy in Agriculture (CENA), University of São Paulo (USP), Piracicaba 13416-000, SP, Brazil.
Aquat Toxicol. 2023 Jul;260:106552. doi: 10.1016/j.aquatox.2023.106552. Epub 2023 May 12.
The expanding use of hybrid nanomaterials in many applications necessitates evaluation of their environmental risks. This study investigates the acute toxicity and bioaccumulation of graphene oxide - gold (GO-Au) nanohybrid in neonates (<24 hrs old) of Daphnia magna after exposure to a wide range of concentrations (1-100 mg/L). No significant mortality or immobilisation was observed after the exposure period. Microscopic observation showed an uptake of the nanohybrid and internal damage in the gut of the exposed organisms. Bioaccumulation of the GO-Au nanohybrid also occurred in a concentration-dependant manner. Continuous evaluation of the environmental risks from exposure to this nanohybrid and other advanced materials is imperative to avert disruption to the ecosystem.
在许多应用中，混合纳米材料的使用不断扩大，因此需要评估它们的环境风险。本研究调查了在暴露于一系列浓度（1-100mg/L）后，大弹涂鱼新生儿（<24 小时龄）中氧化石墨烯-金（GO-Au）纳米杂种的急性毒性和生物累积。暴露期后，未观察到明显的死亡率或固定化。显微镜观察显示，纳米杂种被吸收，暴露生物的肠道内部受损。GO-Au 纳米杂种的生物累积也呈浓度依赖性。必须持续评估暴露于这种纳米杂种和其他先进材料的环境风险，以避免对生态系统造成破坏。
