经外周支气管针吸引导肺结节针尖式冷冻活检术：病例报告。
Peripheral transbronchial needle aspiration-guided pinpoint cryobiopsy of lung nodule without bronchus sign: A case report.
机构信息
Division of Respiratory Medicine, Department of Medicine, Sarawak General Hospital, Ministry of Health Malaysia, Kuching, Sarawak, Malaysia.
Medical Department, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Malaysia.
出版信息
Respir Investig. 2023 Jul;61(4):473-477. doi: 10.1016/j.resinv.2023.04.003. Epub 2023 May 12.
Peripheral transbronchial needle aspiration (pTBNA) allows the access of pulmonary nodules without bronchus sign but is limited to cytological examination. A 39-year-old man with left parotid carcinoma presented with an incidental lung nodule. Target localisation was performed with manual airway mapping, virtual bronchoscopic navigation, and pTBNA. Direct target validation using radial endobronchial ultrasound (rEBUS) was performed through the puncture defect. Targeted pinpoint biopsy with a 1.1 mm cryoprobe through the pTBNA puncture defect confirmed metastatic adenoid cystic carcinoma. Guided pTBNA with rEBUS validation followed by cryobiopsy of lung nodules without bronchus sign is potentially feasible for histological and molecular analyses.
经支气管肺外周穿刺活检术（pTBNA）可用于无支气管征的肺结节，但其仅能进行细胞学检查。一名 39 岁男性，因左侧腮腺癌就诊，发现肺部偶然出现结节。通过手动气道绘图、虚拟支气管镜导航和 pTBNA 进行目标定位。通过 pTBNA 穿刺点进行径向支气管内超声（rEBUS）直接目标验证。通过 pTBNA 穿刺点的 1.1mm 冷冻探针进行靶向微活检，证实为转移性腺样囊性癌。对于无支气管征的肺结节，通过 rEBUS 验证引导 pTBNA 并进行冷冻活检，可能有助于进行组织学和分子分析。
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