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人类半规管的上皮衬里。一项扫描和透射电子显微镜研究。

Epithelial linings of the human semicircular canal. A scanning and transmission electron microscopic study.

作者信息

Nakai Y, Cho H, Miki Y, Cho J S, Hakuba A

出版信息

Arch Otorhinolaryngol. 1986;243(2):77-82. doi: 10.1007/BF00453754.

DOI:10.1007/BF00453754
PMID:3718327
Abstract

We have used scanning and transmission electron microscopy to examine adult human semicircular canals taken at autopsy and an operation. Our findings can be summarized as follows. In the semicircular circular canals obtained at autopsy from a 30-year-old male, non-sensory ciliated cells having 50-60 cilia were seen sporadically in the canal side of the ampulla of the horizontal canal. A labyrinthine specimen taken at operation demonstrated folding of the cell membrane at the base of columnar cells lining the wall of that part of the canal close to the ampulla. Distal to this site, canal wall cells became progressively flattened and their intracytoplasmic organelles were seen to be progressively less abundant. These cells were found to be layered, facing the endolymphatic space. Dense filaments and fibrocytes were present outside these cells, between which were interposed single-layered basement membranes. Since the capillary network present was found to be sparse, we believe that the portion of the canal studied does not produce endolymph but plays a role in the maintenance of the composition of endolymph and perilymph.

摘要

我们利用扫描电子显微镜和透射电子显微镜,对取自尸检和手术的成人人类半规管进行了检查。我们的发现总结如下。在一名30岁男性尸检获得的半规管中,在水平半规管壶腹的管侧偶尔可见有50 - 60根纤毛的非感觉性纤毛细胞。一份手术获取的迷路标本显示,在靠近壶腹的管的该部分壁内衬的柱状细胞基部,细胞膜出现折叠。在该部位远端,管壁细胞逐渐变扁平,其胞质内细胞器逐渐减少。发现这些细胞呈层状,面向内淋巴间隙。在这些细胞外部存在致密细丝和纤维细胞,其间夹有单层基底膜。由于发现存在的毛细血管网络稀疏,我们认为所研究的管段不产生内淋巴,而是在维持内淋巴和外淋巴的成分方面发挥作用。

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1
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Arch Otorhinolaryngol. 1986;243(2):77-82. doi: 10.1007/BF00453754.
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The effects of perilymphatic tonicity on endolymph composition and synaptic activity at the frog semicircular canal.外淋巴张力对青蛙半规管内淋巴成分及突触活动的影响。
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本文引用的文献

1
Scanning electron microscopic observation of the foetal labyrinthine vestibule.胎儿迷路前庭的扫描电子显微镜观察。
Acta Otolaryngol. 1982 May-Jun;93(5-6):349-54. doi: 10.3109/00016488209130892.
2
Cochlear development. Some electron microscopic observations of maturation of hair cells, spiral ganglion and Reissner's membrane.耳蜗发育。关于毛细胞、螺旋神经节和瑞氏膜成熟的一些电子显微镜观察
Acta Otolaryngol. 1968 Nov;66(5):369-85. doi: 10.3109/00016486809126303.
3
Distribution, structure, and function of dark cells in the vestibular labyrinth.
前庭迷路中暗细胞的分布、结构和功能。
Ann Otol Rhinol Laryngol. 1969 Jun;78(3):542-61. doi: 10.1177/000348946907800311.
4
Cilia in the lateral membranous canal (an unexpected electron microscope finding).外侧膜性管中的纤毛(一项意外的电子显微镜检查发现)。
J Laryngol Otol. 1972 Aug;86(8):807-13.
5
Unusual ciliated cell group in the utricle of a cat.猫椭圆囊内异常的纤毛细胞群。
Ann Otol Rhinol Laryngol. 1974 Jan-Feb;83(1):102-6. doi: 10.1177/000348947408300116.
6
Vestibular endolymph-producing epithelium. Electron microscopic study of the development and histochemistry of the dark cells of the crista ampullaris.前庭内淋巴生成上皮。壶腹嵴暗细胞发育及组织化学的电子显微镜研究。
Acta Otolaryngol. 1968 Jul-Aug;66(1):120-8. doi: 10.3109/00016486809126280.
7
Electron microscopic studies of adenosine triphosphatase activity in the stria vascularis and spiral ligament.血管纹和螺旋韧带中三磷酸腺苷酶活性的电子显微镜研究。
Acta Otolaryngol. 1966 Oct-Nov;62(4):411-28. doi: 10.3109/00016486609119586.