Zhongshan Hospital, Medical College of Xiamen University, Xiamen, China.
Lab Med. 2024 Jan 6;55(1):56-61. doi: 10.1093/labmed/lmad035.
The mortality and morbidity rates in children with lower respiratory tract infection (LRTI) remain high.
To describe the number of bacteria that is associated with leukocytes in differential diagnosis of bacterial, mycoplasma, and viral LRTI in children.
Sputum smears were Gram stained for counting single-morphology bacteria associated with leukocytes. The differential diagnostic values of bacterial number were assessed in children with LRTI.
The area under the receiver operating characteristic (ROC) curve was 0.95 for bacterial number in the differential diagnosis of bacterial infection from mycoplasma and viral infections. The area under the ROC curve was 0.62 for procalcitonin and 0.94 for bacterial number in the differential diagnosis of bacterial infection from mycoplasma infection.
The number of bacteria associated with leukocytes in sputum was valuable and rapid in differential diagnosis of bacterial infection in children with suspected bacterial, mycoplasma, and viral LRTI.
下呼吸道感染（LRTI）患儿的病死率和发病率仍然很高。
描述与白细胞相关的细菌数量在儿童细菌性、支原体性和病毒性 LRTI 鉴别诊断中的作用。
对痰液涂片进行革兰氏染色，以计算与白细胞相关的单一形态细菌数量。评估了 LRTI 患儿中细菌数量的鉴别诊断价值。
细菌数量在鉴别细菌性感染与支原体和病毒性感染方面的受试者工作特征（ROC）曲线下面积为 0.95。降钙素原和细菌数量在鉴别细菌性感染与支原体感染方面的 ROC 曲线下面积分别为 0.62 和 0.94。
痰中与白细胞相关的细菌数量在疑似细菌性、支原体性和病毒性 LRTI 患儿的细菌性感染鉴别诊断中具有快速、有价值的作用。
