Yao H, Ekou A, Ehouman E, Guezo M, Soya E, Kouadio D, Touré C, Kipenge R, Koffi D, N'Guetta R
Institut de Cardiologie d'Abidjan, 01 BP V 206 Abidjan, Côte d'Ivoire.
Ann Cardiol Angeiol (Paris). 2023 Jun;72(3):101602. doi: 10.1016/j.ancard.2023.101602. Epub 2023 May 13.
Hypertension is a major risk factor for cardiovascular events. The cardiovascular risk assessment is performed using specific algorithms, particularly SCORE2 and SCORE2-OP developed by the European Society of Cardiology.
Prospective cohort study from February 1, 2022, to July 31, 2022, enrolling 410 hypertensive patients. Epidemiological, paraclinical, therapeutic, and follow-up data were analyzed. Cardiovascular risk stratification of patients was performed using SCORE2 and SCORE2-OP algorithms. We compared the initial and 6-month cardiovascular risks.
The mean age of the patients was 60.88 ± 12.35 years with a female predominance (sex ratio = 0.66). In addition to hypertension, dyslipidemia (45.4%) was the most frequently associated risk factor. A high proportion of patients were classified as high (48.6%) and very high (46.3%) cardiovascular risk, with a significant difference between men and women. Reassessment of cardiovascular risk after 6 months of treatment found significant differences compared with the initial cardiovascular risk (p < 0.001). The rate of patients at low to moderate cardiovascular risk (49.5%) increased substantially, whereas the proportion of patients at very high risk decreased (6.8%).
Our study conducted at Abidjan Heart Institute in a young population of patients with hypertension revealed a severe cardiovascular risk profile. Almost half of the patients are classified at very high cardiovascular risk, based on the SCORE2 and SCORE2-OP. The widespread use of these new algorithms for risk stratification should lead to more aggressive management and prevention strategies for hypertension and associated risk factors.
高血压是心血管事件的主要危险因素。心血管风险评估使用特定算法进行，特别是欧洲心脏病学会开发的SCORE2和SCORE2-OP。
2022年2月1日至2022年7月31日的前瞻性队列研究，纳入410例高血压患者。分析了流行病学、辅助临床、治疗和随访数据。使用SCORE2和SCORE2-OP算法对患者进行心血管风险分层。我们比较了初始和6个月时的心血管风险。
患者的平均年龄为60.88±12.35岁，女性占优势（性别比=0.66）。除高血压外，血脂异常（45.4%）是最常见的相关危险因素。高比例患者被归类为心血管风险高（48.6%）和非常高（46.3%），男性和女性之间存在显著差异。治疗6个月后心血管风险的重新评估发现与初始心血管风险相比有显著差异（p<0.001）。低至中度心血管风险患者的比例（49.5%）大幅增加，而极高风险患者的比例下降（6.8%）。
我们在阿比让心脏研究所对年轻高血压患者群体进行的研究显示出严重的心血管风险状况。根据SCORE2和SCORE2-OP，几乎一半的患者被归类为心血管风险非常高。这些新的风险分层算法的广泛应用应会导致对高血压及相关危险因素采取更积极的管理和预防策略。
