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接受腹膜后机器人辅助腹腔镜肾盂成形术的儿童日间手术:安全可行吗?

Day Surgery in Children Undergoing Retroperitoneal Robot-assisted Laparoscopic Pyeloplasty: Is It Safe and Feasible?

作者信息

Broch Aline, Paye-Jaouen Annabel, Bruneau Beatrice, Glenisson Mathilde, Taghavi Kiarash, Botto Nathalie, Goulin Jeanne, Lopez Pauline, Querciagrossa Stefania, El Ghoneimi Alaa, Dahmani Souhayl, Hidalgo Mary, Blanc Thomas

机构信息

Department of Pediatric Surgery and Urology, Hôpital Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris, Paris, France.

Department of Pediatric Surgery and Urology, National Reference Center for Rare Urinary Tract Malformations (MARVU), University Hospital Robert-Debre, Assistance Publique-Hôpitaux de Paris, Paris, France.

出版信息

Eur Urol Open Sci. 2023 Mar 31;51:55-61. doi: 10.1016/j.euros.2023.03.004. eCollection 2023 May.

Abstract

BACKGROUND

Robot-assisted pyeloplasty is the most frequently performed robotic procedure in children. A retroperitoneal approach limits surgical trauma and avoids peritoneal irritation. This led to the establishment of the criteria for day surgery (DS) and a related clinical care pathway.

OBJECTIVE

To assess the feasibility and safety of DS in children undergoing retroperitoneal robot-assisted laparoscopic pyeloplasty (R-RALP).

DESIGN SETTING AND PARTICIPANTS

We performed a bicentric prospective study (NCT03274050) over 2 yr involving the two major paediatric urology teaching hospitals in Paris. A clinical pathway and a prospective research protocol were specifically established.

INTERVENTION

DS in selected children undergoing R-RALP.

OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS

The primary outcomes were DS failure, 30-d complications, and readmission rates. The secondary outcomes included preoperative characteristics, perioperative parameters, and surgical outcomes. Quantitative variables were expressed as medians with interquartile ranges.

RESULTS AND LIMITATIONS

Thirty-two children fulfilled specific inclusion criteria and were consecutively selected for DS following R-RALP. The median patient age was 7.6 yr (4.1-11.8) and weight 25 kg (14-45). The median console time was 137 min (108-167). There were no intraoperative complications or conversions. Six children were kept under observation overnight and discharged the following day due to persistent pain ( = 3), parental anxiety ( = 2), or a prolonged procedure ( = 1). The median duration of hospital stay of the 26 children in the DS setting was 12.7 h (12.2-13.2). During the 30-d period, there were four emergency room visits (15%) resulting in two patients requiring readmission (8%): one for febrile urinary tract infection (Clavien-Dindo II) and one child with no JJ stent for urinoma (Clavien-Dindo IIIb). Radiological studies confirmed improvement in dilatation for all cases with no recurrence (median follow-up: 15 mo).

CONCLUSIONS

This prospective case series is the first to demonstrate the feasibility and safety of DS in children undergoing R-RALP, obviating the need for routine inpatient care. Excellent results can be achieved by careful patient selection, a clear clinical pathway, and a dedicated team. Further evaluation is warranted to assess the cost effectiveness.

PATIENT SUMMARY

This study shows that day surgery after robotic pyeloplasty is both safe and effective in selected children.

摘要

背景

机器人辅助肾盂成形术是儿童中最常开展的机器人手术。后腹腔入路可减少手术创伤并避免腹膜刺激。这促使了日间手术(DS)标准及相关临床护理路径的建立。

目的

评估DS在接受后腹腔机器人辅助腹腔镜肾盂成形术(R-RALP)的儿童中的可行性和安全性。

设计、地点和参与者:我们在2年时间里开展了一项双中心前瞻性研究(NCT03274050),涉及巴黎两家主要的儿科泌尿外科教学医院。专门制定了临床路径和前瞻性研究方案。

干预措施

对选定的接受R-RALP的儿童进行DS。

结局测量和统计分析

主要结局为DS失败、30天并发症和再入院率。次要结局包括术前特征、围手术期参数和手术结局。定量变量以中位数及四分位间距表示。

结果和局限性

32名儿童符合特定纳入标准,在R-RALP后连续入选DS。患者中位年龄为7.6岁(4.1-11.8岁),体重25kg(14-45kg)。中位控制台操作时间为137分钟(108-167分钟)。无术中并发症或中转开腹情况。6名儿童因持续疼痛(n=3)、家长焦虑(n=2)或手术时间延长(n=1)而留院观察一晚,次日出院。DS组26名儿童的中位住院时间为12.7小时(12.2-13.2小时)。在30天内,有4次急诊就诊(15%),导致2名患者需要再次入院(8%):1例因发热性尿路感染(Clavien-Dindo II级),1例因无双J管致尿囊肿(Clavien-Dindo IIIb级)。影像学研究证实所有病例的肾盂积水均有改善且无复发(中位随访时间:15个月)。

结论

这个前瞻性病例系列首次证明了DS在接受R-RALP的儿童中的可行性和安全性,无需常规住院治疗。通过仔细的患者选择、清晰的临床路径和专业的团队可取得优异结果。有必要进一步评估其成本效益。

患者总结

本研究表明,机器人肾盂成形术后的日间手术在选定的儿童中既安全又有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c8d/10175732/eff7e7091a3b/gr1.jpg

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