Al Harbi Sadan Mohammed, Al Saif Nasser Mohammed, Mawkili Ahmad, Al Breiki Sarah
Department of Dermatology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Eastern Province, Saudi Arabia.
Clin Cosmet Investig Dermatol. 2023 May 8;16:1203-1207. doi: 10.2147/CCID.S411560. eCollection 2023.
Demodex folliculorum is a common ectoparasite of humans that inhabits follicular infundibulum and sebaceous ducts. Its role in various dermatological diseases is well studied. However, data on demodex-induced skin pigmentation are very limited. A diagnosis of this entity can be easily missed for other causes of facial hyperpigmentation such as melasma, lichen planus pigmentosus, erythema dyschromicum perstans, post-inflammatory hyperpigmentation, and drug-induced hyperpigmentation. Here, we report a case of facial demodicosis-induced skin hyperpigmentation in a 35-year-old Saudi male who is on multiple immunosuppressive agents. He was successfully treated with ivermectin 1% cream and had a dramatic improvement at his 3-month follow-up. Our aim is to shed light on this underdiagnosed cause of facial hyperpigmentation which can be easily diagnosed and followed up by bed side dermoscopic examination and managed effectively by anti-demodectic therapies.
毛囊蠕形螨是一种常见的人体体表寄生虫，寄生于毛囊漏斗部和皮脂腺导管。其在各种皮肤病中的作用已得到充分研究。然而，关于蠕形螨引起皮肤色素沉着的数据非常有限。由于面部色素沉着的其他原因，如黄褐斑、色素性扁平苔藓、持久性色素异常性红斑、炎症后色素沉着和药物性色素沉着，这种情况的诊断很容易被遗漏。在此，我们报告一例35岁沙特男性因面部蠕形螨病导致皮肤色素沉着的病例，该患者正在使用多种免疫抑制剂。他成功接受了1%伊维菌素乳膏治疗，在3个月的随访中病情有显著改善。我们的目的是揭示这种容易被漏诊的面部色素沉着原因，通过床边皮肤镜检查可以轻松诊断和随访，并通过抗蠕形螨治疗有效管理。
