Sazdanovic P S, Milisavljevic S, Milovanovic D R, Jankovic S M, Baskic D, Ignjatovic Ristic, Ruzic Zecevic, Tomic Lucic, Djordjevic N, Jovanovic D, Stojkovic A, Lazarevic T, Begovic Cvetkovic, Kostic M J
Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
University Clinical Centre Kragujevac, Kragujevac, Serbia.
Hippokratia. 2022 Apr-Jun;26(2):62-69.
Our study aimed to identify the total costs of inpatient treatment for coronavirus disease 2019 (COVID-19) in a tertiary institution in Serbia, an upper-middle-income country in Southeast Europe.
An observational, retrospective, cost-of-illness study was performed from the perspective of the National Health Insurance Fund and included a cohort of 78 females and 118 males admitted to the COVID-19 ward units of a tertiary center during the first wave of the pandemic.
The median of the total costs in the non-survivors subgroup (n =43) was 3,279.16 Euros [interquartile range (IQR): 4,023.34; range: 355.20-9,909.61) which is higher than in the survivors (n =153) subgroup 747.10 Euros (IQR: 1,088.21; 46.71-3,265.91). The cut-off value of 156.46 Euros regarding the total costs per day was estimated to have 95.3 % sensitivity and 91.5 % specificity for predicting patients' dismal prognosis, with the area under the curve (AUC) of 0.968 (95 % confidence interval: 0.940-0.996, p <0.001).
Direct medical inpatient treatment costs for COVID-19 represent a significant economic burden. The link between increased costs and an ultimate unfavorable outcome should be further explored.HIPPOKRATIA 2022, 26 (2):62-69.
我们的研究旨在确定塞尔维亚(东南欧的一个中高收入国家)一家三级医疗机构中2019冠状病毒病(COVID-19)住院治疗的总成本。
从国家健康保险基金的角度进行了一项观察性、回顾性疾病成本研究,纳入了在疫情第一波期间入住一家三级中心COVID-19病房的78名女性和118名男性队列。
非幸存者亚组(n = 43)的总成本中位数为3279.16欧元[四分位间距(IQR):4023.34;范围:355.20 - 9909.61],高于幸存者亚组(n = 153)的747.10欧元(IQR:1088.21;46.71 - 3265.91)。估计每日总成本的临界值为156.46欧元时,预测患者不良预后的敏感性为95.3%,特异性为91.5%,曲线下面积(AUC)为0.968(95%置信区间:0.940 - 0.996,p < 0.001)。
COVID-19的直接医疗住院治疗成本构成了重大经济负担。成本增加与最终不良结局之间的联系应进一步探讨。《希波克拉底》2022年,26(2):62 - 全文共69页。 (注:原文最后页码信息表述有误,推测正确应为62 - 69页,已按推测正确内容翻译)