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白内障手术中的透明质酸酶与透明质酸钠

Hyaluronidase and sodium hyaluronate in cataract surgery.

作者信息

Calder I G, Smith V H

出版信息

Br J Ophthalmol. 1986 Jun;70(6):418-20. doi: 10.1136/bjo.70.6.418.

Abstract

The use of sodium hyaluronate in cataract surgery and intraocular lens implantation is often followed by a postoperative rise of intraocular pressure. A trial is described in which 10 patients underwent bilateral cataract extraction and Binkhorst intraocular lens implantation with the use of sodium hyaluronate. The enzyme hyaluronidase was instilled into the anterior chamber of the right eye only, to aid removal of sodium hyaluronate, and resulted in a statistically significant lowering of postoperative intraocular pressure in right eyes compared with left. Other uses of the enzyme are discussed.

摘要

透明质酸钠用于白内障手术和人工晶状体植入术后,眼内压常常会升高。本文描述了一项试验,10例患者在使用透明质酸钠的情况下接受了双侧白内障摘除及宾克霍斯特人工晶状体植入术。仅在右眼前房滴注透明质酸酶以辅助清除透明质酸钠,结果显示,与左眼相比,右眼术后眼内压在统计学上显著降低。文中还讨论了该酶的其他用途。

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本文引用的文献

1
Some effects of injection of hyaluronidase into the anterior chamber.向前房注射透明质酸酶的一些作用。
Am J Ophthalmol. 1950 Jan;33(1):33-44, illust. doi: 10.1016/0002-9394(50)90696-9.
4
Obstruction of aqueous outflow by sodium hyaluronate in enucleated human eyes.
Am J Ophthalmol. 1983 May;95(5):668-72. doi: 10.1016/0002-9394(83)90388-4.
10
Early ocular hypertension after cataract extraction.白内障摘除术后早期眼压升高
Br J Ophthalmol. 1974 Aug;58(8):725-31. doi: 10.1136/bjo.58.8.725.

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