Department of Cardiovascular Medicine, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Sichuan, China.
Department of Endoscopy, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Sichuan, China.
Int Wound J. 2023 Oct;20(8):3324-3330. doi: 10.1111/iwj.14213. Epub 2023 May 15.
A meta-analysis investigation to measure the connotation between perioperative glycemic control (GC) approach and sternal wound infection (SWI) in individuals with diabetes mellitus (DM) experiencing cardiac surgery (CS). A comprehensive literature inspection till February 2023 was applied and 2654 interrelated investigations were reviewed. The 12 chosen investigations enclosed 1564 individuals with DM and CS in the chosen investigations' starting point, 790 of them were using strict GC, and 774 were using moderate GC. Odds ratio (OR) in addition to 95% confidence intervals (CIs) were used to compute the value of the Connotation between the perioperative GC approach and SWI in individuals with DM experiencing CS by the dichotomous and continuous approaches and a fixed or random model. Strict GC had significantly lower SWI (OR, 0.33; 95% CI, -0.22-0.50, P < .001) compared with those with moderate GC in individuals with DM and CS. Strict GC had significantly lower SWI compared with those with moderate GC in individuals with DM and CS. However, caused of the small sample sizes of several chosen investigations for this meta-analysis, care must be exercised when dealing with its values.
一项荟萃分析研究旨在衡量糖尿病患者心脏手术后围手术期血糖控制(GC)方法与胸骨伤口感染(SWI)之间的内涵关系。应用了截至 2023 年 2 月的全面文献检索,并对 2654 项相关研究进行了综述。在研究起点纳入了 1564 例接受心脏手术的糖尿病患者,其中 12 项研究选择了严格 GC,774 例采用了中度 GC。使用二项和连续方法以及固定或随机模型,通过比值比(OR)和 95%置信区间(CI)来计算围手术期 GC 方法与糖尿病患者心脏手术后 SWI 之间的内涵。与中度 GC 相比,严格 GC 可显著降低糖尿病患者心脏手术后的 SWI(OR,0.33;95%CI,-0.22-0.50,P < 0.001)。与中度 GC 相比,严格 GC 可显著降低糖尿病患者心脏手术后的 SWI。然而,由于这项荟萃分析中几项研究的样本量较小,在处理其结果时需谨慎。