Helaakoski Viola, Kaprio Jaakko, Hublin Christer, Ollila Hanna M, Latvala Antti
Institute for Molecular Medicine Finland, HiLIFE, University of Helsinki, Helsinki, Finland.
Finnish Institute of Occupational Health, Helsinki, Finland.
Sleep Adv. 2022 Jul 6;3(1):zpac023. doi: 10.1093/sleepadvances/zpac023. eCollection 2022.
Poor sleep is one of the multiple health issues associated with heavy alcohol consumption. While acute effects of alcohol intake on sleep have been widely investigated, the longitudinal associations remain relatively underexplored. The objective of our research was to shed light on cross-sectional and longitudinal associations between alcohol use and poor sleep quality over time, and to elucidate the role of familial confounding factors in such associations.
Using self-report questionnaire data from the Older Finnish Twin Cohort ( = 13 851), we examined how alcohol consumption and binge drinking are associated with sleep quality during a period of 36 years.
Cross-sectional logistic regression analyses revealed significant associations between poor sleep and alcohol misuse, including heavy and binge drinking, at all four time points (OR range = 1.61-3.37, < .05), suggesting that higher alcohol intake is associated with poor sleep quality over the years. Longitudinal cross-lagged analyses indicated that moderate, heavy and binge drinking predict poor sleep quality (OR range = 1.25-1.76, < .05), but not the reverse. Within-pair analyses suggested that the associations between heavy drinking and poor sleep quality were not fully explained by genetic and environmental influences shared by the co-twins.
In conclusion, our findings support previous literature in that alcohol use is associated with poor sleep quality, such that alcohol use predicts poor sleep quality later in life, but not vice versa, and that the association is not fully explained by familial factors.
睡眠质量差是与大量饮酒相关的多种健康问题之一。虽然酒精摄入对睡眠的急性影响已得到广泛研究，但纵向关联仍相对未被充分探索。我们研究的目的是阐明饮酒与睡眠质量差随时间的横断面和纵向关联，并阐明家族混杂因素在这些关联中的作用。
利用来自芬兰老年双胞胎队列（n = 13851）的自我报告问卷数据，我们研究了在36年期间饮酒和暴饮与睡眠质量之间的关联。
横断面逻辑回归分析显示，在所有四个时间点，睡眠质量差与酒精滥用（包括大量饮酒和暴饮）之间均存在显著关联（OR范围 = 1.61 - 3.37，P <.05），这表明多年来较高的酒精摄入量与睡眠质量差有关。纵向交叉滞后分析表明，中度、大量和暴饮饮酒可预测睡眠质量差（OR范围 = 1.25 - 1.76，P <.05），但反之不然。双胞胎对内分析表明，大量饮酒与睡眠质量差之间的关联不能完全由双胞胎共享的遗传和环境影响来解释。
总之，我们的研究结果支持先前的文献，即饮酒与睡眠质量差有关，饮酒可预测晚年睡眠质量差，但反之不然，并且这种关联不能完全由家族因素来解释。
