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Identification of the C-terminal flanking peptide of preprocholecystokinin in rat brain by a novel radioimmunoassay.

作者信息

Varro A, Dockray G J

出版信息

Brain Res. 1986 Jun 18;376(1):213-6. doi: 10.1016/0006-8993(86)90921-2.

DOI:10.1016/0006-8993(86)90921-2
PMID:3719370
Abstract

The C-terminal flanking peptide of preprocholecystokinin (preproCCK) has been identified in extracts of rat brain using a novel radioimmunoassay. There is a single form of immunoreactive material on gel filtration, ion exchange and reversed-phase HPLC. The C-terminal preproCCK immunoreactivity had a similar pattern of distribution to CCK8 in different regions of rat brain. This assay should help in studies of neuronal CCK biosynthesis.

摘要

相似文献

1
Identification of the C-terminal flanking peptide of preprocholecystokinin in rat brain by a novel radioimmunoassay.
Brain Res. 1986 Jun 18;376(1):213-6. doi: 10.1016/0006-8993(86)90921-2.
2
Preprocholecystokinin mRNA in rat brain: regional expression includes thalamus.
Brain Res. 1988 Nov;464(3):247-53. doi: 10.1016/0169-328x(88)90031-9.
3
Isolation, structure and properties of the C-terminal flanking peptide of preprocholecystokinin from rat brain.大鼠脑前胰高血糖素原C端侧翼肽的分离、结构与性质
FEBS Lett. 1986 Aug 18;204(2):386-90. doi: 10.1016/0014-5793(86)80849-3.
4
Expression of the cholecystokinin gene in rat brain during development.
Dev Neurosci. 1987;9(1):61-7. doi: 10.1159/000111609.
5
Regional differences in the development of cholecystokinin-like activity in rat brain.大鼠脑内胆囊收缩素样活性发展的区域差异。
Brain Res. 1983 Sep;285(3):347-52. doi: 10.1016/0165-3806(83)90031-7.
6
An amino-terminal fragment of cholecystokinin-58 is present in the gut: evidence for a similar processing site of procholecystokinin in canine gut and brain.
Regul Pept. 1988 Aug;22(3):205-15. doi: 10.1016/0167-0115(88)90033-x.
7
Prohormone convertase 1 (PC1) when expressed with pro cholecystokinin (pro CCK) in L cells performs three endoproteolytic cleavages which are observed in rat brain and in CCK-expressing endocrine cells in culture, including the production of glycine and arginine extended CCK8.
Biochem Biophys Res Commun. 1998 Jul 30;248(3):538-41. doi: 10.1006/bbrc.1998.9006.
8
Peptides in rat brain immunoreactive for the carboxyl terminal extension of cholecystokinin: distribution and chromatography.大鼠脑中对胆囊收缩素羧基末端延伸具有免疫反应性的肽:分布与色谱分析
Peptides. 1985 Sep-Oct;6(5):857-60. doi: 10.1016/0196-9781(85)90314-6.
9
Is the C-terminal flanking peptide of rat cholecystokinin double sulphated?大鼠胆囊收缩素的C末端侧翼肽是双硫酸化的吗?
FEBS Lett. 1986 Feb 3;196(1):5-8. doi: 10.1016/0014-5793(86)80203-4.
10
Chemical characterization of rat cholecystokinin-58.
Peptides. 1988 Nov-Dec;9(6):1255-60. doi: 10.1016/0196-9781(88)90189-1.

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Expression of the cholecystokinin gene in pediatric tumors.胆囊收缩素基因在儿科肿瘤中的表达。
Proc Natl Acad Sci U S A. 1992 Jul 1;89(13):5819-23. doi: 10.1073/pnas.89.13.5819.