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视频皮肤镜在眼部蠕形螨病患者评估中的应用

Videodermoscopy in the Assessment of Patients With Ocular Demodicosis.

作者信息

Sławińska Martyna, Jaworska Karolina, Wyszomirski Adam, Rychlik Katarzyna, Nowicki Roman Janusz, Sobjanek Michał

机构信息

Department of Dermatology, Venereology and Allergology, Faculty of Medicine, Medical University of Gdańsk, Gdańsk, Poland.

Department of Ophthalmology, Faculty of Medicine, Medical University of Gdańsk, Gdańsk, Poland.

出版信息

Dermatol Pract Concept. 2023 Apr 1;13(2). doi: 10.5826/dpc.1302a109.

DOI:10.5826/dpc.1302a109
PMID:37196309
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10188154/
Abstract

INTRODUCTION

There is growing evidence of the potential uses of dermoscopy in diagnostics of demodicosis. No previous studies have analyzed dermoscopic features in patients with ocular demodicosis.

OBJECTIVES

To evaluate the potential usefulness of videodermoscopy in diagnostics of ocular demodicosis.

METHODS

It was a single-center prospective observational study in which results of videodermoscopic examination of the eyelids were compared to the results of classic microscopic examination in patients with suspected ocular demodicosis and healthy volunteers.

RESULTS

Study group included 16 women and 15 men. In fifteen (48.4%) patients, microbiological examination of epilated eyelashes was positive. The results of forms filled by the patients concerning known subjective clinical symptoms of ocular demodicosis revealed no significant differences between the group with positive and negative results of microscopic examination. The presence of Demodex tails and madarosis observed during dermoscopic assessment correlated positively with positive results of microscopic examination. At least one Demodex tail was found in 86.7% (13/15) cases with positive results of microscopic examination. In the two remaining cases microscopic evaluation showed the presence of Demodex brevis. In 37.5% (6/16) of patients with negative results of microscopic examination, videodermoscopy showed the presence of Demodex tails.

CONCLUSIONS

Videodermoscopy may facilitate the diagnostics of ocular demodicosis. Patients reporting clinical symptoms suggesting ocular demodicosis but negative results of videodermoscopic examination should be referred to classical microscopic examination to exclude the presence of Demodex brevis. In patients with negative microscopic examination results and symptoms suggesting ocular demodicosis, dermoscopy-guided microscopic re-evaluation could be considered.

摘要

引言

越来越多的证据表明皮肤镜检查在蠕形螨病诊断中具有潜在用途。此前尚无研究分析过眼部蠕形螨病患者的皮肤镜特征。

目的

评估视频皮肤镜检查在眼部蠕形螨病诊断中的潜在效用。

方法

这是一项单中心前瞻性观察性研究,将疑似眼部蠕形螨病患者及健康志愿者眼睑的视频皮肤镜检查结果与经典显微镜检查结果进行比较。

结果

研究组包括16名女性和15名男性。15名(48.4%)患者拔除睫毛的微生物学检查呈阳性。患者填写的有关眼部蠕形螨病已知主观临床症状的表格结果显示,显微镜检查结果为阳性和阴性的两组之间无显著差异。皮肤镜评估中观察到的蠕形螨尾部和睫毛脱落与显微镜检查的阳性结果呈正相关。在显微镜检查结果为阳性的病例中,86.7%(13/15)至少发现一条蠕形螨尾部。在其余两例中,显微镜评估显示存在短蠕形螨。在显微镜检查结果为阴性的患者中,37.5%(6/16)的视频皮肤镜检查显示存在蠕形螨尾部。

结论

视频皮肤镜检查可能有助于眼部蠕形螨病的诊断。报告有提示眼部蠕形螨病临床症状但视频皮肤镜检查结果为阴性的患者应进行经典显微镜检查,以排除短蠕形螨的存在。对于显微镜检查结果为阴性但有提示眼部蠕形螨病症状的患者,可考虑进行皮肤镜引导下的显微镜重新评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed84/10188154/16c54192d498/dp1302a109g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed84/10188154/16c54192d498/dp1302a109g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed84/10188154/16c54192d498/dp1302a109g001.jpg

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本文引用的文献

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J Am Acad Dermatol. 2023 Mar;88(3):e127-e128. doi: 10.1016/j.jaad.2021.07.031. Epub 2021 Jul 27.
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Dermoscopic Findings of Rosacea and Demodicosis.酒渣鼻和蠕形螨病的皮肤镜表现
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Dermoscopy of papulopustular rosacea and comparison of dermoscopic features in patients with or without concomitant Demodex folliculorum.酒渣鼻丘疹脓疱期的皮肤镜表现及伴有或不伴有蠕形螨的患者的皮肤镜特征比较。
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Indian Dermatol Online J. 2021 Mar 2;12(2):220-236. doi: 10.4103/idoj.IDOJ_559_20. eCollection 2021 Mar-Apr.
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Scale and Pustule on Dermoscopy of Rosacea: A Diagnostic Clue for Demodex Species.酒渣鼻皮肤镜检查中的鳞屑和脓疱:毛囊蠕形螨种类的诊断线索
Dermatol Pract Concept. 2021 Jan 29;11(1):e2021139. doi: 10.5826/dpc.1101a139. eCollection 2021 Jan.
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The role of dermoscopy in diagnostics of dermatological conditions of the eyelid, eyelashes, and conjunctiva - a literature review.皮肤镜在诊断眼睑、睫毛和结膜的皮肤科疾病中的作用——文献综述。
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Clin Exp Optom. 2021 Apr;104(3):285-294. doi: 10.1111/cxo.13123. Epub 2021 Apr 1.
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Ocular Demodex: a systematic review of the clinical literature.眼部蠕形螨:临床文献的系统评价。
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Clin Exp Dermatol. 2021 Mar;46(2):355-356. doi: 10.1111/ced.14375. Epub 2020 Aug 26.
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