Department of Molecular Virology, Institute of Bioorganic Chemistry Polish Academy of Sciences, Poznan, Poland.
Aquanet Laboratorium, Poznan, Poland.
Int J Infect Dis. 2023 Aug;133:75-77. doi: 10.1016/j.ijid.2023.05.014. Epub 2023 May 15.
Wastewater-based epidemiology can determine the scale of a mpox epidemic and thus is a promising additional tool that can complete data gathered by the clinical monitoring approach and predict more accurately the development and progress of the current mpox outbreak.
We collected daily average samples from two wastewater treatment plants (WTPs): Central and Left-Bank, in Poznan, Poland from July to December 2022. The mpox DNA was detected using real-time polymerase chain reaction and compared with the number of hospitalizations.
We detected the mpox DNA in the Central WTP in weeks 29, 43, and 47 and the Left-Bank WTP mostly from mid-September till the end of October. A total of 22 patients with mpox were reported by the public health authority from July to December 2022, with the highest number of hospitalized individuals from mid-July to mid-August. The mpox virus detection does not correlate with the number of hospitalizations in Poznan, Poland.
Our results suggest that the scale of the mpox epidemic is underestimated, and many mpox virus-infected individuals are not identified by the public health authority.
基于污水的流行病学可以确定猴痘疫情的规模，因此是一种很有前途的补充工具，可以完善临床监测方法收集的数据，并更准确地预测当前猴痘疫情的发展和进程。
我们从波兰波兹南的两个污水处理厂（中央和左岸）收集了 2022 年 7 月至 12 月的每日平均样本。使用实时聚合酶链反应检测猴痘 DNA，并与住院人数进行比较。
我们在第 29、43 和 47 周检测到中央污水处理厂的猴痘 DNA，而左岸污水处理厂主要从 9 月中旬持续到 10 月底。2022 年 7 月至 12 月，公共卫生当局共报告了 22 例猴痘病例，住院人数最多的是 7 月中旬至 8 月中旬。波兰波兹南的猴痘病毒检测与住院人数无关。
我们的结果表明，猴痘疫情的规模被低估了，许多猴痘病毒感染个体未被公共卫生当局发现。
