Gao Cong, Guo Xiaozhong, Li Hongyu, Chen Hongxin, Gao Zhenjiao, Gao Fei, Qi Xingshun
Department of Gastroenterology, General Hospital of Northern Theater Command, Shenyang, China.
Postgraduate College, Dalian Medical University, Dalian, China.
Transl Gastroenterol Hepatol. 2022 May 5;8:21. doi: 10.21037/tgh-22-14. eCollection 2023.
Small intestinal Dieulafoy's lesion (DL) is a rare cause of life-threatening gastrointestinal bleeding. Based on previous case reports, the diagnostic approaches for DL located in jejunum and ileum are different. In addition, there is no available consensus regarding the treatment of DL, and previous case reports suggest that surgery is the preferable choice for small intestinal DL compared to endoscopic treatment. Notably, our case report indicates that double-balloon enteroscopy (DBE) should be an effective diagnostic and therapeutic approach for small intestinal DL.
A 66-year-old female was transferred to the Department of Gastroenterology due to hematochezia and abdominal distension and pain for more than 10 days. She had a history of diabetes, hypertension, coronary heart disease, atrial fibrillation, mitral insufficiency, and acute cerebral infarction. Conventional diagnostic approaches, including gastroduodenoscopy, colonoscopy, and even angiogram, did not show any definite source of bleeding, and then a capsule endoscopy was performed and suggested that the bleeding may be located in ileum. Finally, she was successfully treated by hemostatic clips under DBE via anal route. And there is no recurrence after endoscopic treatment was observed in our case during a 4-month follow-up.
Although small intestinal DL is rare and difficult to be detected by conventional approaches, DL still needs to be considered as a differential diagnosis for gastrointestinal bleeding. In addition, DBE should be considered as a preferred choice for the diagnosis and treatment of small intestinal DL due to lower invasiveness and cost as compared to surgery.
小肠迪厄拉富瓦病(DL)是危及生命的胃肠道出血的罕见原因。根据既往病例报告,位于空肠和回肠的DL的诊断方法有所不同。此外,关于DL的治疗尚无共识,既往病例报告表明,与内镜治疗相比,手术是小肠DL的首选治疗方法。值得注意的是,我们的病例报告表明,双气囊小肠镜检查(DBE)应是小肠DL有效的诊断和治疗方法。
一名66岁女性因便血、腹胀及腹痛10余天转入消化内科。她有糖尿病、高血压、冠心病、心房颤动、二尖瓣关闭不全和急性脑梗死病史。包括胃镜、结肠镜甚至血管造影在内的传统诊断方法均未显示明确的出血源,随后进行了胶囊内镜检查,提示出血可能位于回肠。最后,通过经肛门途径在DBE下用止血夹成功治疗了她。在我们的病例中,内镜治疗后4个月的随访中未观察到复发。
尽管小肠DL罕见且常规方法难以检测,但DL仍需作为胃肠道出血的鉴别诊断考虑。此外,与手术相比,DBE因其侵入性较低和成本较低,应被视为小肠DL诊断和治疗的首选方法。