Knight Cardiovascular Institute and Division of Endocrinology, Diabetes, and Clinical Nutrition, Oregon Health & Science University, Mailcode: HRC5N, 3181 Southwest Sam Jackson Park Road, Portland, OR 97239, USA.
Gastroenterol Clin North Am. 2023 Jun;52(2):261-275. doi: 10.1016/j.gtc.2023.03.001. Epub 2023 Apr 7.
Advances in the understanding of weight regulation provide the framework for the recognition of obesity as a chronic disease. Lifestyle approaches are foundational in the prevention of obesity and should be continued while weight management interventions, including antiobesity medications and metabolic-bariatric procedures, are offered to eligible patients. Clinical challenges remain, however, including overcoming obesity stigma and bias within the medical community toward medical and surgical approaches, ensuring insurance coverage for obesity management (including medications and surgery), and promoting policies that reverse the upward worldwide trend in obesity and adiposity complications in populations.
对体重调节的认识进展为将肥胖认定为一种慢性疾病提供了框架。生活方式方法是预防肥胖的基础，在为符合条件的患者提供体重管理干预措施（包括抗肥胖药物和代谢减重手术）时，应继续采用这些方法。然而，临床挑战依然存在，包括克服肥胖在医疗界的污名和偏见，以及对肥胖管理（包括药物和手术）的保险覆盖，促进扭转全球肥胖和肥胖相关并发症上升趋势的政策。
