Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, The Johns Hopkins University School of Medicine, 550 North Broadway, Suite 1003, Baltimore, MD, 21205, USA.
Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Surg Endosc. 2023 Aug;37(8):6308-6314. doi: 10.1007/s00464-023-10129-3. Epub 2023 May 17.
Controlled radial expansion (CRE) balloon dilators are traditionally used to dilate esophageal strictures during an esophagogastroduodenoscopy (EGD). EndoFLIP is a diagnostic tool used during an EGD to measure important parameters of the gastrointestinal lumen, capable of assessing treatment before and after dilation. EsoFLIP is a related device that combines a balloon dilator with high-resolution impedance planimetry to provide some of the luminal parameters in real time during dilation. We sought to compare procedure time, fluoroscopy time, and safety profile of esophageal dilation using either CRE balloon dilation combined with EndoFLIP (E + CRE) versus EsoFLIP alone.
A single-center retrospective review was performed to identify patients ≤ 21 years of age who underwent an EGD with biopsy and esophageal stricture dilation using E + CRE or EsoFLIP between October 2017 and May 2022.
Twenty-nine EGDs with esophageal stricture dilation were performed in 23 patients (19 E + CRE and 10 EsoFLIP). The two groups did not differ in age, gender, race, chief complaint, type of esophageal stricture, or history of prior gastrointestinal procedures (all p > 0.05). The most common medical history in the E + CRE and EsoFLIP groups were eosinophilic esophagitis and epidermolysis bullosa, respectively. Median procedures times were shorter in the EsoFLIP cohort compared to E + CRE balloon dilation (40.5 min [IQR 23-57 min] for the EsoFLIP group; 64 min [IQR 51-77 min] for the E + CRE group; p < 0.01). Median fluoroscopy times were also shorter for patients who underwent EsoFLIP (0.16 min [IQR 0-0.30 min] for EsoFLIP dilation; 0.30 min [IQR 0.23-0.55] for the E + CRE group; p = 0.003). There were no complications or unplanned hospitalizations in either group.
EsoFLIP dilation of esophageal strictures was faster and required less fluoroscopy than CRE balloon dilation combined with EndoFLIP in children, while being equally as safe. Prospective studies are needed to further compare the two modalities.
在食管胃十二指肠镜检查(EGD)期间,传统上使用受控径向扩张(CRE)球囊扩张器来扩张食管狭窄。EndoFLIP 是一种在 EGD 期间使用的诊断工具,用于测量胃肠道管腔的重要参数,能够在扩张前后评估治疗效果。EsoFLIP 是一种相关设备,它将球囊扩张器与高分辨率阻抗平面测量法结合在一起,在扩张过程中实时提供一些管腔参数。我们旨在比较使用 CRE 球囊扩张联合 EndoFLIP(E+CRE)与单独使用 EsoFLIP 进行食管扩张的手术时间、透视时间和安全性。
对 2017 年 10 月至 2022 年 5 月期间在单中心接受 EGD 检查并伴有活检和食管狭窄扩张的年龄≤21 岁的患者进行了一项回顾性研究,这些患者使用 E+CRE 或 EsoFLIP 进行食管狭窄扩张。
在 23 名患者中进行了 29 次 EGD 伴食管狭窄扩张(19 次 E+CRE 和 10 次 EsoFLIP)。两组在年龄、性别、种族、主要症状、食管狭窄类型或既往胃肠操作史方面无差异(均 p>0.05)。E+CRE 和 EsoFLIP 组中最常见的病史分别为嗜酸性食管炎和大疱性表皮松解症。EsoFLIP 组的手术时间中位数明显短于 E+CRE 球囊扩张组(EsoFLIP 组 40.5 分钟[IQR 23-57 分钟];E+CRE 组 64 分钟[IQR 51-77 分钟];p<0.01)。接受 EsoFLIP 扩张的患者透视时间中位数也较短(EsoFLIP 扩张组 0.16 分钟[IQR 0-0.30 分钟];E+CRE 组 0.30 分钟[IQR 0.23-0.55 分钟];p=0.003)。两组均无并发症或计划外住院。
与 CRE 球囊扩张联合 EndoFLIP 相比,EsoFLIP 扩张儿童食管狭窄的速度更快,透视时间更短,且安全性相当。需要前瞻性研究进一步比较这两种方法。