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非荧光内镜下扩张治疗消化道结核相关狭窄的安全性和有效性。

Safety and efficacy of non-fluoroscopic endoscopic dilatation of gastrointestinal tuberculosis related strictures.

机构信息

Departments of Gastroenterology, Gastrointestinal Surgery and Radiodiagnosis, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

出版信息

BMC Gastroenterol. 2022 Feb 11;22(1):60. doi: 10.1186/s12876-022-02140-0.

Abstract

INTRODUCTION

Stricturing gastrointestinal tuberculosis (GITB) may result in persistent symptoms even after antitubercular therapy (ATT) and may require surgical intervention. Data on efficacy and safety of endoscopic dilatation for management GITB related strictures is scarce.

METHODS

A retrospective analysis of database of patients who underwent endoscopic balloon dilatation for suspected or proven gastrointestinal tuberculosis was performed. The analysis included the site of involvement, technical success, clinical success (response), relapse and requirement of surgery in these patients.

RESULTS

Out of 34 patients (47.1% males, mean age 31.9 ± 12.9 years), eventually four patients were diagnosed to have Crohn's disease while the rest had GITB. Initial technical success was achieved in 30 (88.2%) patients. Initial clinical success was achieved in 28 (82.3%) patients. Median number of dilatation sessions required to obtain symptomatic relief were 2.5 (1-5) per patient. Two patients with initial clinical success had recurrence of symptoms over follow up of 1 year, out of which one patient was managed with repeat endoscopic balloon dilatation successfully. Of 30 patients with technical success, 16 (53.4%) were on ATT when they underwent dilatation while two were in intestinal obstruction. Eventually 7 patients required surgical intervention for various reasons.

CONCLUSION

Non-fluoroscopic endoscopic balloon dilatation is an acceptable and fairly safe modality for symptomatic tuberculous strictures of gastrointestinal tract.

摘要

简介

胃肠道结核(GITB)导致的狭窄即使在抗结核治疗(ATT)后仍可能持续存在症状,可能需要手术干预。关于内镜扩张治疗 GITB 相关狭窄的疗效和安全性的数据很少。

方法

对接受内镜球囊扩张治疗疑似或确诊胃肠道结核的患者数据库进行回顾性分析。该分析包括受累部位、技术成功率、临床成功率(反应)、复发和这些患者对手术的需求。

结果

34 名患者(47.1%为男性,平均年龄 31.9±12.9 岁)中,最终有 4 名被诊断为克罗恩病,其余均为 GITB。初始技术成功率为 30 例(88.2%)。初始临床成功率为 28 例(82.3%)。每位患者获得症状缓解所需的扩张次数中位数为 2.5(1-5)次。28 例初始临床成功的患者中有 2 例在 1 年的随访中出现症状复发,其中 1 例经内镜球囊扩张成功治疗。30 例技术成功的患者中,16 例(53.4%)在接受扩张时正在接受 ATT,2 例有肠梗阻。最终有 7 名患者因各种原因需要手术干预。

结论

非透视内镜球囊扩张是一种可接受的、相当安全的治疗胃肠道结核性狭窄的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/774e/8832754/48f9437a3bc0/12876_2022_2140_Fig1_HTML.jpg

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