CD49d in chronic lymphocytic leukemia: a molecule with multiple regulation layers. Comment to "Sialylation regulates migration in chronic lymphocytic leukemia".
作者信息
Pozzo Federico, Tissino Erika, Zucchetto Antonella, Gattei Valter
机构信息
Clinical and Experimental Onco-Haematology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano.
出版信息
Haematologica. 2024 Jan 1;109(1):362-363. doi: 10.3324/haematol.2023.283237.
Abstract
摘要
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本文引用的文献
1
Sialylation regulates migration in chronic lymphocytic leukemia.
Haematologica. 2023 Jul 1;108(7):1851-1860. doi: 10.3324/haematol.2022.281999.
2
CD49d promotes disease progression in chronic lymphocytic leukemia: new insights from CD49d bimodal expression.
Blood. 2020 Apr 9;135(15):1244-1254. doi: 10.1182/blood.2019003179.
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Sialyltransferase inhibition leads to inhibition of tumor cell interactions with E-selectin, VCAM1, and MADCAM1, and improves survival in a human multiple myeloma mouse model.
Haematologica. 2020 Jan 31;105(2):457-467. doi: 10.3324/haematol.2018.212266. Print 2020.
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Functional and clinical relevance of VLA-4 (CD49d/CD29) in ibrutinib-treated chronic lymphocytic leukemia.
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NOTCH1 mutations are associated with high CD49d expression in chronic lymphocytic leukemia: link between the NOTCH1 and the NF-κB pathways.
Leukemia. 2018 Mar;32(3):654-662. doi: 10.1038/leu.2017.296. Epub 2017 Sep 22.
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CD49d prevails over the novel recurrent mutations as independent prognosticator of overall survival in chronic lymphocytic leukemia.
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CD49d is overexpressed by trisomy 12 chronic lymphocytic leukemia cells: evidence for a methylation-dependent regulation mechanism.
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The CD49d/CD29 complex is physically and functionally associated with CD38 in B-cell chronic lymphocytic leukemia cells.
Leukemia. 2012 Jun;26(6):1301-12. doi: 10.1038/leu.2011.369. Epub 2012 Jan 6.
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CD38 and chronic lymphocytic leukemia: a decade later.
Blood. 2011 Sep 29;118(13):3470-8. doi: 10.1182/blood-2011-06-275610. Epub 2011 Jul 15.
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Surface IgM of CLL cells displays unusual glycans indicative of engagement of antigen in vivo.
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