Centre de Ressource Autisme Languedoc-Roussillon, CHU Montpellier, Montpellier, France; Centre d'Excellence sur l'Autisme et les Troubles du Neurodéveloppement (CeAND), CHU Montpellier, France.
Centre de Ressource Autisme Languedoc-Roussillon, CHU Montpellier, Montpellier, France; Centre d'Excellence sur l'Autisme et les Troubles du Neurodéveloppement (CeAND), CHU Montpellier, France; Université Paris-Saclay, UVSQ, Inserm, CESP, Team DevPsy, 94807, Villejuif, France.
J Psychiatr Res. 2023 Jul;163:43-54. doi: 10.1016/j.jpsychires.2023.05.013. Epub 2023 May 8.
There are strong individual differences in adaptive behaviors (AB) in autism spectrum disorder (ASD) with conflicting results in literature about specific patterns and related factors. The present study aims to describe AB and identify related factors in terms of clinical and socio-familial characteristics in 875 children and adolescents with ASD in the multiregional ELENA cohort in France. Results showed that AB in children and adolescents with ASD were lower than in typically developing subjects, regardless of age group. AB were associated with clinical (gender, age at diagnosis, IQ, ASD severity, psychiatric comorbidities, motor and language skills, challenging behaviors), interventional (school attendance, special interventions) and familial characteristics (age, educational and socio-economic status of parents, household status, number of siblings). There is a need of interventions focusing on improvement of AB, tailored to children's characteristics.
自闭症谱系障碍(ASD)患者的适应行为(AB)存在很大的个体差异,文献中关于具体模式和相关因素的结果相互矛盾。本研究旨在描述法国多区域 ELENA 队列中 875 名 ASD 儿童和青少年的 AB,并根据临床和社会家庭特征确定相关因素。结果表明,无论年龄组如何,ASD 儿童和青少年的 AB 均低于典型发育者。AB 与临床特征(性别、诊断年龄、智商、ASD 严重程度、精神共病、运动和语言技能、挑战性行为)、干预措施(上学、特殊干预)和家庭特征(年龄、父母的教育和社会经济地位、家庭状况、兄弟姐妹数量)有关。需要针对儿童的特点,开展以改善 AB 为重点的干预措施。