步态的光谱参数可将糖尿病患者与健康个体区分开来。

Spectral parameters of gait differentiate diabetic patients from healthy individuals.

机构信息

Centre for Movement, Occupation and Rehabilitation Sciences, Oxford Brookes University, Oxford, UK; University of Maia, Maia, Portugal; Research Center in Sport Science, Health Sciences and Human Development, Vila Real, Portugal.

Centre for Movement, Occupation and Rehabilitation Sciences, Oxford Brookes University, Oxford, UK.

出版信息

Foot (Edinb). 2023 Sep;56:102038. doi: 10.1016/j.foot.2023.102038. Epub 2023 May 8.

DOI:10.1016/j.foot.2023.102038

PMID:37201241

Abstract

BACKGROUND

Diabetes mellitus (DM) is a clinical condition that affects gait performance and control in millions of individuals worldwide. Contrary to basic spatiotemporal parameters, gait-based spectral analysis may provide useful insights into gait neuromotor control. Hence, this study was set to investigate the spectral content of gait at the preferred speed in patients with DM.

METHODS

Total 1117 individuals [658 DM and 649 healthy adults (HA)] performed a 10 m walk while wearing an inertial measurement unit over the fourth lumbar vertebra. Mann-Whitney-U test was used for between-group gait parameters comparisons.

RESULTS

DM group had a slower step time (1.2%, p < 0.05) and gait speed (2.4%, p < 0.05) than HA. Additionally, DM individuals showed reduced dominant frequency (DM:0.24 Hz vs HA:0.25 Hz on average, p < 0.05). Increased antero-posterior and vertical dominant frequency width (DM:1.73 Hz vs HA:1.76 Hz on average, p < 0.05) and medio-lateral relative power spectral density at the dominant frequency (DM:6.19% vs HA:5.96%, p < 0.05).

CONCLUSIONS

It was demonstrated for the first time that the gait spectral content, not only corroborates spatiotemporal characteristics, but also provides further insight into their neuromotor control deficits in diabetic patients. Ultimately, this type of analysis in the diabetic population can help guide the therapeutic interventions to prevent diabetic foot.

摘要

背景

糖尿病（DM）是一种影响全球数百万人步态表现和控制的临床情况。与基本的时空参数不同，基于步态的频谱分析可能为步态神经运动控制提供有用的见解。因此，本研究旨在调查 DM 患者在其惯用速度下的步态频谱内容。

方法

共有 1117 人[658 名 DM 患者和 649 名健康成年人（HA）]在第四腰椎上佩戴惯性测量单元进行 10 米行走。使用 Mann-Whitney-U 检验进行组间步态参数比较。

结果

DM 组的步时（1.2%，p<0.05）和步速（2.4%，p<0.05）均比 HA 慢。此外，DM 个体的主导频率降低（DM：平均 0.24 Hz，HA：平均 0.25 Hz，p<0.05）。前后向和垂直向主导频率宽度增加（DM：平均 1.73 Hz，HA：平均 1.76 Hz，p<0.05）以及在主导频率处的横向相对功率谱密度增加（DM：6.19%，HA：5.96%，p<0.05）。