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[伴有喉部受累的多发性骨髓瘤:一种罕见的声音嘶哑病因]

[Multiple myeloma with laryngeal affectation: an uncommon cause of dysphonia].

作者信息

González Fernández Andrés, Berasategui Fuertes Maider, Sanhueza Torres Ignacio, Larrea Ramírez Alba

机构信息

Servicio de Otorrinolaringología y Cirugía de Cabeza y Cuello. Hospital Universitario de Navarra. Servicio Navarra de Salud-Osasunbidea. Pamplona. Navarra. España..

Servicio de Anatomía Patológica. Hospital Universitario de Navarra. Servicio Navarra de Salud-Osasunbidea. Pamplona. Navarra. España..

出版信息

An Sist Sanit Navar. 2023 Apr 25;46(1):e1034. doi: 10.23938/ASSN.1034.

Abstract

Plasma cell proliferation leads to the formation of a single tumour (plasmacytoma) or to systemic disease (myeloma). Plasma cell myeloma involving laryngeal cartilage is unusual and clinical manifestations are similar to those of laryngeal carcinoma. We report the case of a 70-year-old man with disphonia after a recent diagnosis of multiple myeloma. Radiological and immunohistochemical studies showed laryngeal involvement. The patient is currently under treatment with lenalidomide, dexamethasone, and bortezomib.

摘要

浆细胞增殖会导致单个肿瘤(浆细胞瘤)的形成或全身性疾病(骨髓瘤)。累及喉软骨的浆细胞骨髓瘤并不常见,其临床表现与喉癌相似。我们报告一例70岁男性病例,该患者近期诊断为多发性骨髓瘤后出现声音嘶哑。影像学和免疫组化研究显示喉部受累。该患者目前正在接受来那度胺、地塞米松和硼替佐米治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea53/10208389/1671986acf95/assn-46-01-e1034-g1.jpg

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