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马来西亚砂拉越美里两家基层医疗诊所的高血压患者中阻塞性睡眠呼吸暂停的流行情况及其相关因素。

Prevalence and factors associated with probable obstructive sleep apnea among patients with hypertension in two primary care clinics in Miri, Sarawak, Malaysia.

机构信息

Department of Family Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Malaysia.

Malaysian Research Institute On Ageing, Universiti Putra Malaysia, Serdang, Malaysia.

出版信息

Ir J Med Sci. 2024 Feb;193(1):375-382. doi: 10.1007/s11845-023-03397-4. Epub 2023 May 19.

DOI:10.1007/s11845-023-03397-4
PMID:37204559
Abstract

PURPOSE

Obstructive sleep apnea (OSA) has been increasingly recognized as an important factor contributing to medical morbidity and mortality. It was reported that more than half of the population with hypertension had OSA. Limited studies have been done on assessing OSA in hypertensive patients. This study aimed to determine the prevalence, socio-demographic characteristics, and factors associated with probable OSA in hypertensive patients in primary care clinics in Sarawak.

METHODS

A cross-sectional study was carried out using a systematic random sampling method in hypertensive patients who attended two government primary care clinics in Sarawak. The STOP-Bang questionnaire was used to screen for OSA, and social-demographic data was captured with a questionnaire. Multiple logistic regressions were used to examine the determinants of the OSA.

RESULTS

A total of 410 patients were enrolled in this study. The mean age of study population patients was 56.4 years, with more than half being female. The mean blood pressure was 136/82. The prevalence of probable OSA among patients with hypertension was 54.4%. According to multiple logistic regression analyses, smoking (odds ratio [OR] 14.37, 95% confidence interval [CI] 3.335-61.947), retirees (OR 3.20, 95% CI 1.675-6.113), and being Chinese (OR 2.21, 95% CI 1.262-3.863) had a significant positive association with probable OSA.

CONCLUSIONS

Because of the high prevalence of probable OSA among patients with hypertension, primary care physicians should be more vigilant in identifying hypertensive patients with OSA risk. Early detection and intervention would reduce disease complications and healthcare costs.

摘要

目的

阻塞性睡眠呼吸暂停(OSA)已被越来越多地认为是导致医疗发病率和死亡率的重要因素。据报道,超过一半的高血压患者患有 OSA。对高血压患者的 OSA 评估进行了有限的研究。本研究旨在确定在沙捞越的初级保健诊所中高血压患者中 OSA 的患病率、社会人口统计学特征以及与可能的 OSA 相关的因素。

方法

采用系统随机抽样法对在沙捞越的两家政府初级保健诊所就诊的高血压患者进行横断面研究。使用 STOP-Bang 问卷筛查 OSA,并使用问卷获取社会人口统计学数据。使用多因素逻辑回归分析检查 OSA 的决定因素。

结果

本研究共纳入 410 名患者。研究人群患者的平均年龄为 56.4 岁,其中一半以上为女性。平均血压为 136/82mmHg。高血压患者中可能的 OSA 患病率为 54.4%。根据多因素逻辑回归分析,吸烟(比值比[OR]14.37,95%置信区间[CI]3.335-61.947)、退休人员(OR 3.20,95% CI 1.675-6.113)和中国人(OR 2.21,95% CI 1.262-3.863)与可能的 OSA 有显著正相关。

结论

由于高血压患者中可能的 OSA 患病率较高,初级保健医生应更加警惕识别有 OSA 风险的高血压患者。早期发现和干预将降低疾病并发症和医疗保健成本。

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