冷沉淀在新生儿中的应用。
Use of Cryoprecipitate in Newborn Infants.
作者信息
Tyagi Manvi, Guaragni Brunetta, Dendi Alvaro, Tekleab Atnafu Mekonnen, Motta Mario, Maheshwari Akhil
机构信息
Department of Pediatrics, Augusta University, Georgia, USA.
Department of Neonatology and Neonatal Intensive Care, Children's Hospital, ASST-Spedali Civili, Brescia, Italy.
出版信息
Newborn (Clarksville). 2023 Jan-Mar;2(1):11-18. doi: 10.5005/jp-journals-11002-0045. Epub 2023 Apr 6.
Cryoprecipitate is a transfusion blood product derived from fresh-frozen plasma (FFP), comprised mainly of the insoluble precipitate that gravitates to the bottom of the container when plasma is thawed and refrozen. It is highly enriched in coagulation factors I (fibrinogen), VIII, and XIII; von Willebrand factor (vWF); and fibronectin. In this article, we have reviewed currently available information on the preparation, properties, and clinical importance of cryoprecipitate in treating critically ill neonates. We have searched extensively in the databases PubMed, Embase, and Scopus after short-listing keywords to describe the current relevance of cryoprecipitate.
冷沉淀是一种从新鲜冷冻血浆（FFP）中提取的输血血液制品，主要由血浆解冻后再冷冻时沉淀在容器底部的不溶性沉淀物组成。它富含凝血因子I（纤维蛋白原）、VIII和XIII；血管性血友病因子（vWF）；以及纤连蛋白。在本文中，我们回顾了目前关于冷沉淀在治疗危重新生儿时的制备、特性和临床重要性的可用信息。在筛选出描述冷沉淀当前相关性的关键词后，我们在PubMed、Embase和Scopus数据库中进行了广泛搜索。
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